Pseudomonas aeruginosa is a pathogen often encountered in a healthcare setting. It has
consistently ranked among the most frequent pathogens seen in nosocomial infections …

Antimicrobial resistance represents a serious threat for global health, causing an
unacceptable burden in terms of morbidity, mortality and healthcare costs. In particular, in …

Carbapenem resistance in difficult-to-treat P. aeruginosa (DTR-PA) strains is primarily
mediated by loss or reduction of the OprD porin, overexpression of the cephalosporinase …

This objective of this study was to compare clinical outcomes in hospitalized patients with
Pseudomonas aeruginosa pneumonia (PNA) or bloodstream infection (BSI) receiving beta …

Aim To investigate the efficacy of intravenous (IV) fosfomycin as combination therapy for
treatment of difficult-to-treat (DTT) acute and subacute infections with multi-drug-resistant …

Nosocomial infections caused by non-fermenting Gram-negative bacteria are a real
challenge for clinicians, especially concerning the accuracy of empirical treatment. This …

Objectives To use a pre-clinical pharmacokinetic infection model to assess the antibacterial
effect of ceftolozane/tazobactam alone or in combination with fosfomycin or tobramycin …

Purpose This executive summary of a German national guideline aims to provide the most
relevant evidence-based recommendations on the diagnosis and treatment of nosocomial …

Background Fluoroquinolones are one of the commonly used antibiotics for the initial
empiric combination treatment. However, there is insufficient evidence to support the use of …

Background: Pseudomonas aeruginosa (PA) is a major public health community-acquired
threat around the globe due to the growing rate of antimicrobial resistance. It is one of the …