BACKGROUND The authors attempted to resolve the dilemma posed by the lack of
unanimity concerning the optimal immunohistochemical (IHC) method for determining and …

To visualize the heterogeneity of androgen receptor (AR) and progesterone receptor (PR)
expression in ovarian tumors, 61 specimens were studied immunohistochemically using …

Immunohistochemical methods have enjoyed rapid growth in application and utility since
their initial adaptation to paraffin sections 20 years ago. Initial applications were directed …

BACKGROUND The measurement of estrogen receptors (ER) in breast cancer specimens
has traditionally been assessed with a dextran‐coated charcoal assay (DCCA). More …

Steroid hormone receptors and reactivity for Ki‐67 proliferation antigen were studied
immunohistochemically in non‐neoplastic post‐menopausal human ovary and in 29 ovarian …

This study was undertaken to evaluate our abilityto detect multiple molecular markers of
prognosis andresponse to treatment in fine needle aspirates (FNA) from patients with …

Estrogen receptor (ER) analysis in breast cancer has been used in three clinical situations:
to select patients with advanced breast cancer for hormonal therapy, as a prognostic …

Traditionally, cancer prognostication has been based on the histological typing and clinical
staging of the tumour. However, these parameters do not adequately identify subsets of …

Tumor markers are certain products produced either by the tumor itself or by the body in
response to a tumor, which can be of benign or malignant type. Identification of prognostic …