Abstract Bisphenol A (BPA; 4, 4′-isopropylidenediphenol) is an endocrine disruptor that is
used as a material for the production of phenol resins, polyacrylates, polyesters, epoxy …

In women, the non-growing population of follicles that comprise the ovarian reserve is
determined at birth and serves as the reservoir for future fertility. This reserve of dormant …

The dynamic transcriptional regulation and interactions of human germlines and
surrounding somatic cells during folliculogenesis remain unknown. Using RNA sequencing …

BACKGROUND The first small follicles to appear in the mammalian ovaries are primordial
follicles. The initial pool of primordial follicles serves as the source of developing follicles …

Zinc is a critical component in a number of conserved processes that regulate female germ
cell growth, fertility, and pregnancy. During follicle development, a sufficient intracellular …

In women, ovary and adrenal gland produce androgens. Androgens are essential drivers of
the primordial to antral follicle development, prior to serving as substrate for estrogen …

Humans are exposed daily to di (2-ethylhexyl) phthalate (DEHP), a plasticizer found in many
consumer, medical, and building products containing polyvinyl chloride. Large doses of …

Among the components of the female reproductive tract, the ovarian pool of follicles and
their enclosed oocytes are highly sensitive to hyperthermia. Heat-induced alterations in …

The female germline comprises a reserve population of primordial (non-growing) follicles
containing diplotene oocytes arrested in the first meiotic prophase. By convention, the …

Ovarian follicle pool depletion, infertility, and premature menopause are all known sequelae
of cancer treatment that negatively impact the quality of life of young cancer survivors. The …