Crosstalk between mitochondrial dysfunction, oxidative stress, and age related neurodegenerative disease: Etiologies and therapeutic strategies

HA Elfawy, B Das - Life sciences, 2019 - Elsevier
Mitochondrial function is vital for normal cellular processes. Mitochondrial damage and
oxidative stress have been greatly implicated in the progression of aging, along with the …

NADPH oxidase in brain injury and neurodegenerative disorders

MW Ma, J Wang, Q Zhang, R Wang… - Molecular …, 2017 - Springer
Oxidative stress is a common denominator in the pathology of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral …

Food antioxidants: chemical insights at the molecular level

A Galano, G Mazzone, R Alvarez-Diduk… - Annual review of …, 2016 - annualreviews.org
In this review, we briefly summarize the reliability of the density functional theory (DFT)-
based methods to accurately predict the main antioxidant properties and the reaction …

Neuroprotective properties of berberine: Molecular mechanisms and clinical implications

E Tian, G Sharma, C Dai - Antioxidants, 2023 - mdpi.com
Berberine (BBR), an isoquinoline alkaloid natural product, is isolated primarily from Coptis
chinensis and other Berberis plants. BBR possesses various bioactivities, including …

Development of early diagnosis of Parkinson's disease: Illusion or reality?

M Ugrumov - CNS neuroscience & therapeutics, 2020 - Wiley Online Library
The fight against neurodegenerative diseases, Alzheimer disease and Parkinson's disease
(PD), is a challenge of the 21st century. The low efficacy of treating patients is due to the late …

Lawsonia Inermis Markedly Improves Cognitive Functions in Animal Models and Modulate Oxidative Stress Markers in the Brain

NT Mir, U Saleem, F Anwar, B Ahmad, I Ullah, S Hira… - Medicina, 2019 - mdpi.com
Background and Objective: Medicinal plants represent an important source of alternative
medicine for the management of various diseases. The present study was undertaken to …

Emerging novel approaches for the enhanced delivery of natural products for the management of neurodegenerative diseases

A Bandiwadekar, J Jose, M Khayatkashani… - Journal of Molecular …, 2022 - Springer
Neurodegenerative diseases (NDs) such as Alzheimer's disease, Parkinson's disease,
Huntington disease, amyotrophic lateral sclerosis, and prion disease affect any part of the …

Synaptosomes: new vesicles for neuronal mitochondrial transplantation

P Picone, G Porcelli, CC Bavisotto, D Nuzzo… - Journal of …, 2021 - Springer
Background Mitochondrial dysfunction is a critical factor in the onset and progression of
neurodegenerative diseases. Recently, mitochondrial transplantation has been advised as …

Trends in electrochemical nanosensors for the analysis of antioxidants

R Nimal, O Selcuk, S Kurbanoglu, A Shah… - TrAC Trends in …, 2022 - Elsevier
Antioxidants play a very critical role in many biological processes in which free radicals are
present. The physiological part of these compounds prevents damage to cellular …

The tragedy of Alzheimer's disease: towards better management via resveratrol-loaded oral bilosomes

H Abbas, HA Gad, MA Khattab, M Mansour - Pharmaceutics, 2021 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease where oxidative stress plays a
major role as a key pathologic factor. The study aims to develop resveratrol (RES)-loaded …