Steroidal saponins: naturally occurring compounds as inhibitors of the hallmarks of cancer

S Bouabdallah, A Al-Maktoum, A Amin - Cancers, 2023 - mdpi.com
Simple Summary Cancer is one of the most life-threatening diseases that affects a rapidly
growing number of individuals worldwide. Currently, chemotherapy is the most common …

Biosynthesis of gold and silver nanoparticles using phytochemical compounds

A Zuhrotun, DJ Oktaviani, AN Hasanah - Molecules, 2023 - mdpi.com
Gold and silver nanoparticles are nanoparticles that have been widely used in various fields
and have shown good benefits. The method of nanoparticle biosynthesis utilizing plant …

Anticancer potential of the plant‐derived Saponin Gracillin: a comprehensive review of mechanistic approaches

MS Bhuia, R Chowdhury, FA Sonia… - Chemistry & …, 2023 - Wiley Online Library
With the increasing prevalence of cancer and the toxic side effects of synthetic drugs, natural
products are being developed as promising therapeutic approaches. Gracillin is a naturally …

[HTML][HTML] Doxorubicin-loaded Niosomes functionalized with gelatine and alginate as pH-responsive drug delivery system: A 3D printing approach

M Zaer, A Moeinzadeh, H Abolhassani… - International Journal of …, 2023 - Elsevier
Despite many efforts, breast cancer remains one of the deadliest cancers and its treatment
faces challenges related to cancer drug side effects and metastasis. Combining 3D printing …

DNA damage and its role in cancer therapeutics

J Moon, I Kitty, K Renata, S Qin, F Zhao… - International Journal of …, 2023 - mdpi.com
DNA damage is a double-edged sword in cancer cells. On the one hand, DNA damage
exacerbates gene mutation frequency and cancer risk. Mutations in key DNA repair genes …

[HTML][HTML] Core-shell inorganic NPs@ MOF nanostructures for targeted drug delivery and multimodal imaging-guided combination tumor treatment

S Khan, M Falahati, WC Cho, Y Vahdani… - Advances in Colloid and …, 2023 - Elsevier
It is well known that metal-organic-framework (MOF) nanostructures have unique
characteristics such as high porosity, large surface areas, and adjustable biofunctionalities …

New insights in aptamer-targeted nanoliposomes for the treatment of breast cancer

NJ Singhai, R Maheshwari, K Khatri - Journal of Drug Delivery Science and …, 2023 - Elsevier
Despite significant advances in understanding breast cancer pathogenesis and prognosis, it
remains one of the most common causes of death for women worldwide. To develop a more …

Spermine‐Responsive intracellular self‐aggregation of gold nanocages for enhanced chemotherapy and photothermal therapy of breast cancer

B Xie, H Zhao, M Shui, YF Ding, C Sun, Z Wang, C Gao… - Small, 2022 - Wiley Online Library
Improving the precise accumulation and retention of nanomedicines in tumor cells is one of
the keys to effective therapy of tumors. Herein, supramolecular peptides capped Au …

[HTML][HTML] Bimetallic nanoparticles as suitable nanocarriers in cancer therapy

H Makada, S Habib, M Singh - Scientific African, 2023 - Elsevier
Cancer is a widespread disease which has been prevalent for decades and for which a cure
is yet to be discovered. Current treatments are fraught with severe side effects to patients …

Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming

IS Pateras, C Williams, DD Gianniou… - Journal of Translational …, 2023 - Springer
Background Chemotherapy (CT) is central to the treatment of triple negative breast cancer
(TNBC), but drug toxicity and resistance place strong restrictions on treatment regimes …