Mechanisms, management, and treatment of fibrosis in patients with inflammatory bowel diseases
F Rieder, C Fiocchi, G Rogler - Gastroenterology, 2017 - Elsevier
In the last 10 years, we have learned much about the pathogenesis, diagnosis, and
management of intestinal fibrosis in patients with inflammatory bowel diseases. Just a …
management of intestinal fibrosis in patients with inflammatory bowel diseases. Just a …
Crohn's disease
J Torres, S Mehandru, JF Colombel, L Peyrin-Biroulet - The Lancet, 2017 - thelancet.com
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract, with
increasing incidence worldwide. Crohn's disease might result from a complex interplay …
increasing incidence worldwide. Crohn's disease might result from a complex interplay …
Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease
FM Ruemmele, G Veres, KL Kolho… - Journal of Crohn's …, 2014 - academic.oup.com
Children and adolescents with Crohn's disease (CD) present often with a more complicated
disease course compared to adult patients. In addition, the potential impact of CD on growth …
disease course compared to adult patients. In addition, the potential impact of CD on growth …
Deep remission at 1 year prevents progression of early Crohn's disease
Background & Aims We investigated the effects of inducing deep remission in patients with
early Crohn's disease (CD). Methods We collected follow-up data from 122 patients (mean …
early Crohn's disease (CD). Methods We collected follow-up data from 122 patients (mean …
Personalised medicine in Crohn's disease
Similar to many immune-mediated diseases, Crohn's disease follows a relapsing-remitting
pattern, with a variable disease course and heterogeneous clinical outcomes. Frequency of …
pattern, with a variable disease course and heterogeneous clinical outcomes. Frequency of …
Pathogenesis of fibrostenosing Crohn's disease
Crohn's disease (CD) is a chronic inflammatory disease, which could affect any part of the
gastrointestinal tract. A severe complication of CD is fibrosis-associated strictures, which can …
gastrointestinal tract. A severe complication of CD is fibrosis-associated strictures, which can …
Fibrosis in IBD: from pathogenesis to therapeutic targets
F Rieder, PK Mukherjee, WJ Massey, Y Wang… - Gut, 2024 - gut.bmj.com
Background Intestinal fibrosis resulting in stricture formation and obstruction in Crohn's
disease (CD) and increased wall stiffness leading to symptoms in ulcerative colitis (UC) is …
disease (CD) and increased wall stiffness leading to symptoms in ulcerative colitis (UC) is …
[HTML][HTML] Use of biologics for the management of Crohn's disease: IG-IBD clinical guidelines based on the GRADE methodology
FS Macaluso, C Papi, A Orlando, S Festa… - Digestive and Liver …, 2023 - Elsevier
A cure for Crohn's disease (CD), a chronic inflammatory disease of the gastrointestinal tract
of unknown etiology, is not available, so patients require lifelong management to keep …
of unknown etiology, is not available, so patients require lifelong management to keep …
[HTML][HTML] Association between level of fecal calprotectin and progression of Crohn's disease
NA Kennedy, GR Jones, N Plevris, R Patenden… - Clinical …, 2019 - Elsevier
Background & Aims Mucosal healing is associated with improved outcomes in patients with
Crohn's disease (CD), but assessment typically requires ileocolonoscopy. Calprotectin can …
Crohn's disease (CD), but assessment typically requires ileocolonoscopy. Calprotectin can …
The disease severity index for inflammatory bowel disease is associated with psychological symptoms and quality of life, and predicts a more complicated disease …
A Swaminathan, D Fan, GM Borichevsky… - Alimentary …, 2022 - Wiley Online Library
Summary Background The Disease Severity Index (DSI) is a novel tool to predict disease
severity in inflammatory bowel disease (IBD). However, its ability to predict disease …
severity in inflammatory bowel disease (IBD). However, its ability to predict disease …