Copper is an indispensable trace metal element in the human body, which is mainly
absorbed in the stomach and small intestine and excreted into the bile. Copper is an …

Clinical studies, as well as in vitro and in vivo experiments have demonstrated that
byproducts from joint replacements induce an inflammatory reaction that can result in …

Implant-related infections are serious complications after bone surgery and can compromise
the intended functions of artificial implants, leading to surgical failure and even amputation …

In biomaterials science, it is nowadays well accepted that improving the biointegration of
dental and orthopedic implants with surrounding tissues is a major goal. However, implant …

Titanium and its alloys are dominant material for orthopedic/dental implants due to their
stable chemical properties and good biocompatibility. However, aseptic loosening and peri …

Background: The search for potential markers for a timely and accurate diagnosis of
periprosthetic joint infection (PJI) is ongoing. Previous studies have focused on inflammatory …

Background: Genicular artery embolization (GAE) is a novel therapy to treat patients with
symptomatic knee osteoarthritis (OA) by reducing synovial arterial hypervascularity. This …

Background: Total joint arthroplasty (TJA) episodic payment models shift risk and cost of
periprosthetic joint infection (PJI) to surgeons and hospitals, causing some to avoid treating …

To fix the bone in orthopedics, it is almost always necessary to use implants. Metals provide
the needed physical and mechanical properties for load-bearing applications. Although …

Abstract 3D printed porous titanium alloy implants is an advanced orthopedic material for
joint replacement. However, the high risk of aseptic loosening and periprosthetic infection is …