Invasive lobular carcinoma (ILC) is the most common of the breast cancer special types,
accounting for up to 15% of all breast cancer cases. ILCs are noted for their lack of E …

Breast cancer is the most prevalent malignant tumor and main oncologic cause of mortality
in women. Although most diagnosis of breast pathology is accomplished using hematoxylin …

Breast lesions with uncertain malignant behavior, also known as high-risk or B3 lesions, are
composed of a variety of pathologies with differing risks of associated malignancy. While …

Recent studies have reported germline CDH1 mutations in cases of lobular breast cancer
(LBC) not associated with the classical hereditary diffuse gastric cancer syndrome. A …

Accurate pathological diagnosis is the cornerstone of optimal clinical management for
patients with breast disease. As non‐operative diagnosis has now become the standard of …

More than 10% of breast biopsies performed based on findings at mammography yield
highrisk lesions (HRLs). 1 HRLs refer to a group of heterogeneous lesions that can be …

Abstract Background Pleomorphic and Florid Lobular carcinoma in situ (P/F LCIS) are rare
variants of LCIS, the exact nature of which is still debated. Aim To collect a large series of …

E-cadherin complexes with the actin cytoskeleton via cytoplasmic catenins and maintains
the functional characteristics and integrity of the epithelia in normal epithelial tissues. Lost …

Abstract Evaluation of radiologically detected breast lesions is a common task in surgical
pathology. Some benign lesions on biopsy are associated with an upgrade to in situ or …

Many similar characteristics in human and dog cancers including, spontaneous
development, clinical presentation, tumor heterogeneity, disease progression, and response …