Tumor metastasis to bone is a common event in multiple forms of malignancy. Inflammation
holds essential functions in homeostasis as a defense mechanism against infections and is …

Purpose Bone marrow adipocytes (BMAs) are the most plentiful cells in the bone marrow
and function as an endocrine organ by producing fatty acids, cytokines, and adipokines …

Breast cancer (BC) patient prognosis has improved over the past 2 decades with a 99% 5-
year survival rate for localized BC, yet metastatic breast cancer (mBC) continues to cause …

Bone marrow adipocytes (BMAs) represent 10% of the total fat mass of the human body and
serve as an energy reservoir for the skeletal niche. They function as an endocrine organ by …

Cirsium japonicum var. maackii (Maxim.) Matsum. or Korean thistle flower is a herbal plant
used to treat tumors in Korean folk remedies, but its essential bioactives and …

When compared to adipocytes in other anatomical sites, the interaction of bone marrow
resident adipocytes with the other cells in their microenvironment is less well understood …

Cancer metastasis, or the development of secondary tumors in distant tissues, accounts for
the vast majority of fatalities in patients with breast cancer. Breast cancer cells show a …

Blood urea nitrogen (BUN) was an important biomarker for the development and prognosis
of many diseases. Numerous studies had demonstrated that BUN had a strong relationship …

Simple Summary Breast cancer cells travel via the bloodstream to the bone before the
cancer is detectable in the breast. These disseminated cells are resistant to adjuvant …

Simple Summary Breast cancers that express estrogen receptor alpha (ER+) are the most
common subtype of breast cancers. Although surgery and anti-estrogen therapies are …