Biofilms are microbial aggregation membranes that are formed when microorganisms attach
to the surfaces of living or nonliving things. Importantly, biofilm properties provide …

Infections are a growing global threat, and the number of resistant species of microbial
pathogens is alarming. However, the rapid development of cross-resistant or multidrug …

It has been demonstrated that some non-steroidal anti-inflammatory drugs (NSAIDs), like
acetylsalicylic acid, diclofenac, and ibuprofen, have anti-biofilm activity in concentrations …

The global spread of microbial resistance coupled with high costs and slow pace in the
discovery of a new antibiotic have made drug repositioning an attractive and promising …

Antibacterial resistance poses a critical public health threat, challenging the prevention and
treatment of bacterial infections. The search for innovative antibacterial agents has spurred …

Persistent infections, usually associated with biofilm-producing bacteria, are challenging for
both medical and scientific communities. The potential interest in drug repurposing for …

Drug discovery and development are long and financially taxing processes. On an average
it takes 12–15 years and costs 1.2 billion USD for successful drug discovery and approval …

The treatment of bacterial infections has been troubled by the increased resistance to
antibiotics, instigating the search for new antimicrobial therapies. Phytochemicals have …

Aim There is a need to explore new alternatives for root canal disinfection in regenerative
endodontics, since the current strategies are far from ideal. Currently, the potential use of …

This review outlines a literature‐based approach with illustrative examples of drug
repurposing (one molecule, multiple targets), which will be useful in tackling the problem of …