miRNA dosage control in development and human disease
In mammals, miRNAs recognize target mRNAs via base pairing, which leads to a complex
'multiple-to-multiple'regulatory network. Previous studies have focused on the regulatory …
'multiple-to-multiple'regulatory network. Previous studies have focused on the regulatory …
RNA-binding proteins and cancer metastasis
S Wang, Z Sun, Z Lei, HT Zhang - Seminars in cancer biology, 2022 - Elsevier
RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …
[HTML][HTML] RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer
Traditionally majority of eukaryotic gene expression is influenced by transcriptional and post-
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …
[HTML][HTML] RNA-binding proteins hold key roles in function, dysfunction, and disease
S Kelaini, C Chan, VA Cornelius, A Margariti - Biology, 2021 - mdpi.com
Simple Summary Chronic hyperglycemia manifests in a variety of different micro-and
macrovascular disorders such as diabetes mellitus and cardiovascular disease and has …
macrovascular disorders such as diabetes mellitus and cardiovascular disease and has …
LncRNA SNHG12 in extracellular vesicles derived from carcinoma-associated fibroblasts promotes cisplatin resistance in non-small cell lung cancer cells
D Tan, G Li, P Zhang, C Peng, B He - Bioengineered, 2022 - Taylor & Francis
Non-small-cell lung cancer (NSCLC) is defined as the most universally diagnosed class of
lung cancer. Cisplatin (DDP) is an effective drug for NSCLC, but tumors are prone to drug …
lung cancer. Cisplatin (DDP) is an effective drug for NSCLC, but tumors are prone to drug …
Overview of the miR-29 family members' function in breast cancer
M Amirian, AM Jafari-Nozad, M Darroudi… - International Journal of …, 2023 - Elsevier
Accumulating evidence has indicated the importance of microRNAs (miRs) in the biology of
human malignancies by targeting multiple signaling pathways and different Messenger RNA …
human malignancies by targeting multiple signaling pathways and different Messenger RNA …
[HTML][HTML] MEX3A promotes the malignant progression of ovarian cancer by regulating intron retention in TIMELESS
F Li, C Zhao, Y Diao, Z Wang, J Peng, N Yang… - Cell Death & …, 2022 - nature.com
The latest research shows that RNA-binding proteins (RBPs) could serve as novel potential
targets for cancer therapy. We used bioinformatics analysis to screen and identify the key …
targets for cancer therapy. We used bioinformatics analysis to screen and identify the key …
[HTML][HTML] RNA binding protein: coordinated expression between the nuclear and mitochondrial genomes in tumors
J Ma, L Sun, W Gao, Y Li, D Dong - Journal of Translational Medicine, 2023 - Springer
Mitochondria are the only organelles regulated by two genomes. The coordinated
translation of nuclear DNA (nDNA) and mitochondrial DNA (mtDNA), which together co …
translation of nuclear DNA (nDNA) and mitochondrial DNA (mtDNA), which together co …
An ERK1/2‐driven RNA‐binding switch in nucleolin drives ribosome biogenesis and pancreatic tumorigenesis downstream of RAS oncogene
MS Azman, EL Alard, M Dodel, F Capraro… - The EMBO …, 2023 - embopress.org
Oncogenic RAS signaling reprograms gene expression through both transcriptional and
post‐transcriptional mechanisms. While transcriptional regulation downstream of RAS is …
post‐transcriptional mechanisms. While transcriptional regulation downstream of RAS is …
[HTML][HTML] The function and regulatory mechanism of RNA-binding proteins in breast cancer and their future clinical treatment prospects
X Lu, J Zhong, L Liu, W Zhang, S Zhao, L Chen… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is the most common female malignancy, but the mechanisms regulating gene
expression leading to its development are complex. In recent years, as epigenetic research …
expression leading to its development are complex. In recent years, as epigenetic research …