Dengue is one of the most important mosquito-borne viral diseases that are relentlessly
spreading in newer areas in the tropical and subtropical regions of the World. In last fifty …

The biology of the viral life cycle essentially includes two structural and functional entities—
the viral genome and protein machinery constituting the viral arsenal and an array of host …

Eukaryotic cells adopt highly tuned stress response physiology under threats of exogenous
stressors including viruses to maintain cellular homeostasis. Not surprisingly, avoidance of …

Usutu virus (USUV) is an African mosquito-borne flavivirus closely related to West Nile,
Japanese encephalitis, Zika, and dengue viruses. USUV emerged in 1996 in Europe, where …

Cytoplasmic Processing bodies (P bodies), the RNA-protein aggregation foci of
translationally stalled and potentially decaying mRNA, have been reported to be …

Infection of BHK cells by Sindbis virus (SV) gives rise to a profound inhibition of cellular
protein synthesis, whereas translation of viral subgenomic mRNA that encodes viral …

Viruses are intracellular pathogens and are dependent on host cellular resources to carry
out their cycles of perpetuation. Obtaining an integrative view of host–virus interaction is of …

The integrated stress response (ISR) protects cells from a variety of insults. Once elicited
(eg, by virus infections), it eventually leads to the block of mRNA translation. Central to the …

The rotavirus (RV) non-structural protein NSP3 forms a dimer that has binding domains for
the translation initiation factor eIF4G and for a conserved 3′-terminal sequence of viral …

As obligate parasites, viruses depend on the synthetic machinery of the cell to translate their
proteins and on the cell's energy and building blocks to replicate their genomes. Cells …