Mammalian sperm are deposited in the vagina or the cervix/uterus at coitus or at artificial
insemination, and the fertilizing sperm move through the female reproductive tract to the …

The main cation/calcium channel of spermatozoa (CatSper), first identified in 2001, has
been thoroughly studied to elucidate its composition and function, while its distribution …

Calcium signaling is critical for successful fertilization. In spermatozoa, calcium influx into the
sperm flagella mediated by the sperm-specific CatSper calcium channel is necessary for …

STUDY QUESTION Whether and how do Na+/H+ exchangers (NHEs) regulate the
physiological functions of human sperm? SUMMARY ANSWER NHE-mediated flagellar …

In female tract, mammalian sperm develop hyperactivated motility which is a key
physiological event for sperm to fertilize eggs. This motility change is triggered by Ca 2+ …

After sperm enter the female reproductive tract, the physicochemical and biochemical
microenvironment undergoes significant changes. In particular, the large changes in various …

Infertility is a growing health concern among many couples worldwide. Men account for half
of infertility cases. CatSper, a sperm-specific Ca 2+ channel, is expressed on the cell …

Mammalian spermatogenesis is a highly complicated and intricately organized process
involving spermatogonia propagation (mitosis) and meiotic differentiation into mature sperm …

The in vitro storage of stallion spermatozoa for use in artificial insemination leads to
oxidative stress and imbalances in calcium homeostasis that trigger the formation of the …

Type 2 taste receptors (TAS2Rs), traditionally known for their role in bitter taste perception,
are present in diverse reproductive tissues of both sexes. This review explores our current …