The renin-angiotensin system is one of the major homaeostatic mechanisms regulating
arterial pressure and salt and water balance. 4-6 The renal enzyme renin, reacting with a …

Discussion Fig. 1. Digital subtraction angio gram demonstrating severe bilateral renal artery
stenosis. potassium chloride elixir, 40 mmol every morning. Followup by the hypertension …

Synopsis: Captopril 1 is the first orally active inhibitor of angiotensin-converting enzyme to
become available. It has been studied to date primarily in hypertension. In mild to moderate …

End-stage kidney disease (ESKD), defined as the need for dialysis, receipt of a transplant, or
death from chronic kidney failure, generally affects fewer than 1% of the population …

The purpose of this brief review is to separate the characteristic properties and side effects
attributable to the pharmacology of the whole class of angiotensin converting enzyme (ACE) …

A retrospective study of nine sick premature infants with chronic lung disease who received
captopril for control of systemic hypertension (systolic blood pressure (BP)> 113 mm Hg) …

Angiotensin-converting enzyme inhibitor-induced renal failure is now a well-recognized
phenomenon that appears to occur almost exclusively in patients with a preexisting …

Discussion DR. RANDALL M. ZUSMAN (Director, Hypertension Division, Cardiac Unit,
Massachusetts General Hospital, and Assistant Professor of Medicine, Harvard Medical …

Mitogen-activated protein kinases (MAP kinases) are functionally connected kinases that
regulate key cellular process involved in kidney disease such as all survival, death …

The renal extraction ratios of 131I-sodium iodohippurate (131I-Hippuran) and 125I-
thalamate were greatly reduced on the affected side by 50 mg captopril in seven out of 14 …