Polymeric in situ forming depots for long-acting drug delivery systems
Polymeric in situ forming depots have emerged as highly promising drug delivery systems
for long-acting applications. Their effectiveness is attributed to essential characteristics such …
for long-acting applications. Their effectiveness is attributed to essential characteristics such …
Drug release from in situ forming implants and advances in release testing
X Wang, DJ Burgess - Advanced Drug Delivery Reviews, 2021 - Elsevier
In situ forming implants, defined as liquid formulations that generate solid or semisolid
depots following administration, have shown a range of advantages in drug delivery. This …
depots following administration, have shown a range of advantages in drug delivery. This …
Current trends in PLGA based long-acting injectable products: The industry perspective
OS Muddineti, A Omri - Expert Opinion on Drug Delivery, 2022 - Taylor & Francis
Introduction Poly (lactic-co-glycolic acid)(PLGA) has been used in many long-acting drug
formulations, which have been approved by the US Food and Drug Administration (FDA) …
formulations, which have been approved by the US Food and Drug Administration (FDA) …
A critical review on the microencapsulation of bioactive compounds and their application
K Huang, Y Yuan, X Baojun - Food Reviews International, 2023 - Taylor & Francis
Microencapsulation is an effective method to incorporate environmentally sensitive bioactive
compounds into small capsules to increase stability and bioavailability. The morphological …
compounds into small capsules to increase stability and bioavailability. The morphological …
Microfluidic-assisted nanoprecipitation of biodegradable nanoparticles composed of PTMC/PCL (co) polymers, tannic acid and doxorubicin for cancer treatment
This study was aimed towards the development of a novel microfluidic approach for the
preparation of (co) polymeric and hybrid nanoparticles (NPs) composed of (co) …
preparation of (co) polymeric and hybrid nanoparticles (NPs) composed of (co) …
[HTML][HTML] An in vitro gel-based system for characterizing and predicting the long-term performance of PLGA in situ forming implants
In situ forming implants are exposed to an extracellular matrix resembling a gel rather than
aqueous solution upon subcutaneous administration. The aim of study was to develop a gel …
aqueous solution upon subcutaneous administration. The aim of study was to develop a gel …
A long-acting formulation of rifabutin is effective for prevention and treatment of Mycobacterium tuberculosis
Tuberculosis (TB) is a communicable disease caused by Mycobacterium tuberculosis (Mtb)
and is a major cause of morbidity and mortality. Successful treatment requires strict …
and is a major cause of morbidity and mortality. Successful treatment requires strict …
Nanostructured electrospun polycaprolactone—propolis mats composed of different morphologies for potential use in wound healing
AC De Figueiredo, JM Anaya-Mancipe, AOS De Barros… - Molecules, 2022 - mdpi.com
This study aimed to investigate different types of morphologies obtained using the
electrospinning process to produce a material that enables wound healing while performing …
electrospinning process to produce a material that enables wound healing while performing …
Effects of drug physicochemical properties on in-situ forming implant polymer degradation and drug release kinetics
In-situ forming implants (ISFIs) represent a simple, tunable, and biodegradable polymer-
based platform for long-acting drug delivery. However, drugs with different physicochemical …
based platform for long-acting drug delivery. However, drugs with different physicochemical …
Electrospun Nanofibers Loaded with Plantago major L. Extract for Potential Use in Cutaneous Wound Healing
JM Anaya-Mancipe, VM Queiroz, RF Dos Santos… - Pharmaceutics, 2023 - mdpi.com
Plantago major L. is a plant available worldwide that has been traditionally used for several
medical applications due to its wound healing, anti-inflammatory, and antimicrobial …
medical applications due to its wound healing, anti-inflammatory, and antimicrobial …