Hydrogen Sulfide (H2S) and Polysulfide (H2Sn) Signaling: The First 25 Years

H Kimura - Biomolecules, 2021 - mdpi.com
Since the first description of hydrogen sulfide (H2S) as a toxic gas in 1713 by Bernardino
Ramazzini, most studies on H2S have concentrated on its toxicity. In 1989, Warenycia et al …

A fluorescent probe for fast and quantitative detection of hydrogen sulfide in blood

H Peng, Y Cheng, C Dai, AL King… - Angewandte …, 2011 - Wiley Online Library
Hydrogen sulfide (H2S), well-known for its unpleasant rotten egg smell, was traditionally
considered as a toxic gas. However, recent studies have demonstrated that hydrogen sulfide …

Hydrogen sulphide and its therapeutic potential

C Szabó - Nature reviews Drug discovery, 2007 - nature.com
Hydrogen sulphide (H2S) is increasingly being recognized as an important signalling
molecule in the cardiovascular and nervous systems. The production of H2S from l-cysteine …

Redox biochemistry of hydrogen sulfide

O Kabil, R Banerjee - Journal of Biological Chemistry, 2010 - ASBMB
H 2 S, the most recently discovered gasotransmitter, might in fact be the evolutionary
matriarch of this family, being both ancient and highly reduced. Disruption of γ-cystathionase …

Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production

M Fu, W Zhang, L Wu, G Yang, H Li… - Proceedings of the …, 2012 - National Acad Sciences
Although many types of ancient bacteria and archea rely on hydrogen sulfide (H2S) for their
energy production, eukaryotes generate ATP in an oxygen-dependent fashion. We …

Fluorescent probes for the selective detection of chemical species inside mitochondria

Z Xu, L Xu - Chemical Communications, 2016 - pubs.rsc.org
During the last few years, the preparation of novel fluorescent probes for the selective
detection of chemical species inside mitochondria has attracted considerable attention …

miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1

JX Wang, JQ Jiao, Q Li, B Long, K Wang, JP Liu… - Nature medicine, 2011 - nature.com
Myocardial infarction is a leading cause of mortality worldwide. Here we report that
modulation of microRNA-499 (miR-499) levels affects apoptosis and the severity of …

Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent

AL King, DJ Polhemus, S Bhushan… - Proceedings of the …, 2014 - National Acad Sciences
Previous studies have demonstrated that hydrogen sulfide (H2S) protects against multiple
cardiovascular disease states in a similar manner as nitric oxide (NO). H2S therapy also has …

Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria

Y Kimura, YI Goto, H Kimura - Antioxidants & redox signaling, 2010 - liebertpub.com
Hydrogen sulfide (H2S) is a synaptic modulator as well as a neuroprotectant in the brain. We
recently showed that H2S protects neurons from oxidative stress by increasing the levels of …

3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain

N Shibuya, M Tanaka, M Yoshida… - Antioxidants & redox …, 2009 - liebertpub.com
Hydrogen sulfide (H2S) is a synaptic modulator as well as a neuroprotectant. Currently,
pyridoxal-5′-phosphate (PLP)-dependent cystathionine β-synthase (CBS) is thought to be …