Toward hydrogen sulfide based therapeutics: critical drug delivery and developability issues
Abstract Hydrogen sulfide (H2S), together with nitric oxide (NO) and carbon monoxide (CO),
belongs to the gasotransmitter family and plays important roles in mammals as a signaling …
belongs to the gasotransmitter family and plays important roles in mammals as a signaling …
[HTML][HTML] Thiol reactive probes and chemosensors
Thiols are important molecules in the environment and in biological processes. Cysteine
(Cys), homocysteine (Hcy), glutathione (GSH) and hydrogen sulfide (H2S) play critical roles …
(Cys), homocysteine (Hcy), glutathione (GSH) and hydrogen sulfide (H2S) play critical roles …
[HTML][HTML] Preventing mitochondrial reverse electron transport as a strategy for cardioprotection
In the context of myocardial infarction, the burst of superoxide generated by reverse electron
transport (RET) at complex I in mitochondria is a crucial trigger for damage during …
transport (RET) at complex I in mitochondria is a crucial trigger for damage during …
The quantitative significance of the transsulfuration enzymes for H2S production in murine tissues
O Kabil, V Vitvitsky, P Xie, R Banerjee - 2011 - liebertpub.com
The enzymes of the transsulfuration pathway, cystathionine β-synthase (CBS) and
cystathionine γ-lyase (CSE), are important for the endogenous production of hydrogen …
cystathionine γ-lyase (CSE), are important for the endogenous production of hydrogen …
Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide
Y Mikami, N Shibuya, Y Kimura, N Nagahara… - Biochemical …, 2011 - portlandpress.com
H2S (hydrogen sulfide) has recently been recognized as a signalling molecule as well as a
cytoprotectant. We recently demonstrated that 3MST (3-mercaptopyruvate sulfurtransferase) …
cytoprotectant. We recently demonstrated that 3MST (3-mercaptopyruvate sulfurtransferase) …
A near-infrared fluorescent turn-on probe for fluorescence imaging of hydrogen sulfide in living cells based on thiolysis of dinitrophenyl ether
X Cao, W Lin, K Zheng, L He - Chemical Communications, 2012 - pubs.rsc.org
A near-infrared fluorescent turn-on probe for fluorescence imaging of hydrogen sulfide in living
cells based on thiolysis of dinitrophenyl ether - Chemical Communications (RSC Publishing) …
cells based on thiolysis of dinitrophenyl ether - Chemical Communications (RSC Publishing) …
The emerging role of irisin in cardiovascular diseases
J Fu, F Li, Y Tang, L Cai, C Zeng, Y Yang… - Journal of the American …, 2021 - Am Heart Assoc
Irisin, a novel hormone like polypeptide, is cleaved and secreted by an unknown protease
from a membrane‐spanning protein, FNDC5 (fibronectin type III domain‐containing protein …
from a membrane‐spanning protein, FNDC5 (fibronectin type III domain‐containing protein …
Actions and interactions of nitric oxide, carbon monoxide and hydrogen sulphide in the cardiovascular system and in inflammation—a tale of three gases!
L Li, A Hsu, PK Moore - Pharmacology & therapeutics, 2009 - Elsevier
Nitric oxide (NO), carbon monoxide (CO) and hydrogen sulphide (H2S) together make up a
family of biologically active gases (the so-called 'gaseous triumvirate') with an increasingly …
family of biologically active gases (the so-called 'gaseous triumvirate') with an increasingly …
Hydrogen sulfide in the mammalian cardiovascular system
YH Liu, M Lu, LF Hu, PTH Wong… - Antioxidants & redox …, 2012 - liebertpub.com
For more than a century, hydrogen sulfide (H2S) has been regarded as a toxic gas. This
review surveys the growing recognition of the role of H2S as an endogenous signaling …
review surveys the growing recognition of the role of H2S as an endogenous signaling …
Reactive sulfur species: a new redox player in cardiovascular pathophysiology
Hydrogen sulfide has emerged as an important gaseous signaling molecule and a regulator
of critical biological processes. However, the physiological significance of hydrogen sulfide …
of critical biological processes. However, the physiological significance of hydrogen sulfide …