Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine

M Brown, J Li, C Moraes, M Tabrizian, NYK Li-Jessen - Biomaterials, 2022 - Elsevier
Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …

Progression in translational research on spinal cord injury based on microenvironment imbalance

B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

[HTML][HTML] Bioprinting and regeneration of auricular cartilage using a bioactive bioink based on microporous photocrosslinkable acellular cartilage matrix

L Jia, Y Hua, J Zeng, W Liu, D Wang, G Zhou, X Liu… - Bioactive materials, 2022 - Elsevier
Tissue engineering provides a promising strategy for auricular reconstruction. Although the
first international clinical breakthrough of tissue-engineered auricular reconstruction has …

[HTML][HTML] Dual-crosslinked regenerative hydrogel for sutureless long-term repair of corneal defect

X Shen, S Li, X Zhao, J Han, J Chen, Z Rao, K Zhang… - Bioactive Materials, 2023 - Elsevier
Corneal transplantation is the most effective clinical treatment for corneal defects, but it
requires precise size of donor corneas, surgical sutures, and overcoming other technical …

[HTML][HTML] TGF-β1-supplemented decellularized annulus fibrosus matrix hydrogels promote annulus fibrosus repair

Q Wei, D Liu, G Chu, Q Yu, Z Liu, J Li, Q Meng… - Bioactive Materials, 2023 - Elsevier
Annulus fibrosus (AF) repair remains a challenge because of its limited self-healing ability.
Endogenous repair strategies combining scaffolds and growth factors show great promise in …

Organoids: The current status and biomedical applications

S Yang, H Hu, H Kung, R Zou, Y Dai, Y Hu… - MedComm, 2023 - Wiley Online Library
Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …

Recent advance in bioactive hydrogels for repairing spinal cord injury: material design, biofunctional regulation, and applications

Z Sun, D Zhu, H Zhao, J Liu, P He, X Luan, H Hu… - Journal of …, 2023 - Springer
Functional hydrogels show potential application in repairing spinal cord injury (SCI) due to
their unique chemical, physical, and biological properties and functions. In this …

[HTML][HTML] Multifunctional hydrogel enhances bone regeneration through sustained release of Stromal Cell-Derived Factor-1α and exosomes

L Chen, C Yu, Y Xiong, K Chen, P Liu, AC Panayi… - Bioactive Materials, 2023 - Elsevier
Fracture nonunion remains a great challenge for orthopedic surgeons. Fracture repair
comprises of three phases, the inflammatory, repair and remodeling stage. Extensive …

Decellularized ECM hydrogels: prior use considerations, applications, and opportunities in tissue engineering and biofabrication

J Kort-Mascort, S Flores-Torres, O Peza-Chavez… - Biomaterials …, 2023 - pubs.rsc.org
Tissue development, wound healing, pathogenesis, regeneration, and homeostasis rely
upon coordinated and dynamic spatial and temporal remodeling of extracellular matrix …

Injectable decellularized dental pulp matrix-functionalized hydrogel microspheres for endodontic regeneration

L Zheng, Y Liu, L Jiang, X Wang, Y Chen, L Li, M Song… - Acta Biomaterialia, 2023 - Elsevier
The sufficient imitation of tissue structures and components represents an effective and
promising approach for tissue engineering and regenerative medicine applications. Dental …