Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine
Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …
glycosaminoglycans, and small molecules that are important for the maintenance and repair …
Progression in translational research on spinal cord injury based on microenvironment imbalance
B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …
and imposes a considerable burden on patients, families, and society. Repair of the injured …
[HTML][HTML] Bioprinting and regeneration of auricular cartilage using a bioactive bioink based on microporous photocrosslinkable acellular cartilage matrix
L Jia, Y Hua, J Zeng, W Liu, D Wang, G Zhou, X Liu… - Bioactive materials, 2022 - Elsevier
Tissue engineering provides a promising strategy for auricular reconstruction. Although the
first international clinical breakthrough of tissue-engineered auricular reconstruction has …
first international clinical breakthrough of tissue-engineered auricular reconstruction has …
[HTML][HTML] Dual-crosslinked regenerative hydrogel for sutureless long-term repair of corneal defect
X Shen, S Li, X Zhao, J Han, J Chen, Z Rao, K Zhang… - Bioactive Materials, 2023 - Elsevier
Corneal transplantation is the most effective clinical treatment for corneal defects, but it
requires precise size of donor corneas, surgical sutures, and overcoming other technical …
requires precise size of donor corneas, surgical sutures, and overcoming other technical …
[HTML][HTML] TGF-β1-supplemented decellularized annulus fibrosus matrix hydrogels promote annulus fibrosus repair
Q Wei, D Liu, G Chu, Q Yu, Z Liu, J Li, Q Meng… - Bioactive Materials, 2023 - Elsevier
Annulus fibrosus (AF) repair remains a challenge because of its limited self-healing ability.
Endogenous repair strategies combining scaffolds and growth factors show great promise in …
Endogenous repair strategies combining scaffolds and growth factors show great promise in …
Organoids: The current status and biomedical applications
S Yang, H Hu, H Kung, R Zou, Y Dai, Y Hu… - MedComm, 2023 - Wiley Online Library
Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …
derived from cells with stem potential and can self‐organize and differentiate into 3D cell …
Recent advance in bioactive hydrogels for repairing spinal cord injury: material design, biofunctional regulation, and applications
Z Sun, D Zhu, H Zhao, J Liu, P He, X Luan, H Hu… - Journal of …, 2023 - Springer
Functional hydrogels show potential application in repairing spinal cord injury (SCI) due to
their unique chemical, physical, and biological properties and functions. In this …
their unique chemical, physical, and biological properties and functions. In this …
[HTML][HTML] Multifunctional hydrogel enhances bone regeneration through sustained release of Stromal Cell-Derived Factor-1α and exosomes
L Chen, C Yu, Y Xiong, K Chen, P Liu, AC Panayi… - Bioactive Materials, 2023 - Elsevier
Fracture nonunion remains a great challenge for orthopedic surgeons. Fracture repair
comprises of three phases, the inflammatory, repair and remodeling stage. Extensive …
comprises of three phases, the inflammatory, repair and remodeling stage. Extensive …
Decellularized ECM hydrogels: prior use considerations, applications, and opportunities in tissue engineering and biofabrication
Tissue development, wound healing, pathogenesis, regeneration, and homeostasis rely
upon coordinated and dynamic spatial and temporal remodeling of extracellular matrix …
upon coordinated and dynamic spatial and temporal remodeling of extracellular matrix …
Injectable decellularized dental pulp matrix-functionalized hydrogel microspheres for endodontic regeneration
L Zheng, Y Liu, L Jiang, X Wang, Y Chen, L Li, M Song… - Acta Biomaterialia, 2023 - Elsevier
The sufficient imitation of tissue structures and components represents an effective and
promising approach for tissue engineering and regenerative medicine applications. Dental …
promising approach for tissue engineering and regenerative medicine applications. Dental …