In one decade, immunotherapy based on immune checkpoint blockades (ICBs) has become
a new pillar of cancer treatment following surgery, radiation, chemotherapy, and targeted …

Simple Summary The extensive array of applications in 3D culture models closely mimics
the precise physiological conditions of in vivo settings, enabling the investigation of …

The innate immune sensing of nucleic acids using effective immunoadjuvants is critical for
increasing protective immune responses against cancer. Stimulators of interferon genes …

Background Tamoxifen (TAM) is often recommended as a first‐line treatment for estrogen
receptor‐positive breast cancer (BC). However, TAM resistance continues to be a medical …

Can Vaccines Stop Cancer Before It Starts? Assessing the Promise of Prophylactic
Immunization Against High-Risk Preneoplastic Lesions Loading logo Journals Policies …

New strategies targeting STING proteins appear promising for eliciting immunotherapeutic
responses. Activation of the STING pathway under the right circumstances can drive …

Older patients with cancer, particularly those over 75 years of age, often experience poorer
clinical outcomes compared to younger patients. This can be attributed to age-related …

Chronic stress has a substantial influence on the tumor microenvironment (TME), leading to
compromised effectiveness of anti-cancer therapies through diverse mechanisms. It disrupts …

Nanozymes, which combine enzyme-like catalytic activity and the biological properties of
nanomaterials, have been widely used in biomedical fields. Single-atom nanozymes (SANs) …

Navigating the intricate landscape of the tumor microenvironment (TME) unveils a pivotal
arena for cancer therapeutics, where cytokines and soluble mediators emerge as double …