Aortic aneurysm and dissection are complicated diseases having both high prevalence and
mortality. It is usually diagnosed at advanced stages and posing diagnostic and therapeutic …

Cardiovascular disease is a primary cause of mortality worldwide. Therefore, it is of major
interest to identify sensitive molecular markers that predict cardiovascular events and point …

Objectives Acute aortic dissection (AAD) is a severe clinical emergency with a high mortality,
and is easily misdiagnosed in its early stage. This study aimed at discovering serum …

Sphingomyelin (SM) is a type of sphingolipid found within plasma, cellular membranes and
plasma lipoproteins. Here we highlight the basic biochemical features of SMs and their role …

Aims Thoracic aortic dissection (TAD) is a life-threatening disease with no effective drug
therapy thus far. New therapeutic targets and indications for timely surgical intervention are …

Herein we summarize the current knowledge on the bicuspid aortic valve (BAV)-associated
aortopathy regarding clinical presentation and disease sub-classification, genetic …

Pathogenic mechanisms in degenerative thoracic aortic aneurysms (TAA) are still unclear.
There is an ongoing debate about whether TAAs are caused by uniform or distinct …

Aneurysm is the second-most common disease affecting the aorta worldwide after
atherosclerosis. While several clinical metabolomic studies have been reported, no study …

Thoracic aortic aneurysm (TAA) develops silently and asymptomatically and is a major
cause of mortality. TAA prevalence is greatly underestimated, it is usually diagnosed …

Acute aortic dissection (AAD) is a cardiovascular disease that manifests suddenly and
fatally. Due to the lack of specific early symptoms, many patients with AAD are often …