Overcoming cancer therapeutic bottleneck by drug repurposing
Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated
the development of the alternative strategy of drug repurposing, the development of old …
the development of the alternative strategy of drug repurposing, the development of old …
Determinants of relapse periodicity in Plasmodium vivax malaria
NJ White - Malaria journal, 2011 - Springer
Plasmodium vivax is a major cause of febrile illness in endemic areas of Asia, Central and
South America, and the horn of Africa. Plasmodium vivax infections are characterized by …
South America, and the horn of Africa. Plasmodium vivax infections are characterized by …
Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination
T Bousema, C Drakeley - Clinical microbiology reviews, 2011 - Am Soc Microbiol
Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …
falciparum responsible for the majority of the disease burden and P. vivax being the …
The clinical impact of artemisinin resistance in Southeast Asia and the potential for future spread
CJ Woodrow, NJ White - FEMS microbiology reviews, 2017 - academic.oup.com
Artemisinins are the most rapidly acting of currently available antimalarial drugs. Artesunate
has become the treatment of choice for severe malaria, and artemisinin-based combination …
has become the treatment of choice for severe malaria, and artemisinin-based combination …
Primaquine: the risks and the benefits
Primaquine is the only generally available anti-malarial that prevents relapse in vivax and
ovale malaria, and the only potent gametocytocide in falciparum malaria. Primaquine …
ovale malaria, and the only potent gametocytocide in falciparum malaria. Primaquine …
Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue
SH Adjalley, GL Johnston, T Li… - Proceedings of the …, 2011 - National Acad Sciences
Clinical studies and mathematical models predict that, to achieve malaria elimination,
combination therapies will need to incorporate drugs that block the transmission of …
combination therapies will need to incorporate drugs that block the transmission of …
Triple therapy with artemether–lumefantrine plus amodiaquine versus artemether–lumefantrine alone for artemisinin-resistant, uncomplicated falciparum malaria: an …
Background Late treatment failures after artemisinin-based combination therapies (ACTs) for
falciparum malaria have increased in the Greater Mekong subregion in southeast Asia …
falciparum malaria have increased in the Greater Mekong subregion in southeast Asia …
Reduced Susceptibility of Plasmodium falciparum to Artesunate in Southern Myanmar
Background Plasmodium falciparum resistance to artemisinins, the first line treatment for
malaria worldwide, has been reported in western Cambodia. Resistance is characterized by …
malaria worldwide, has been reported in western Cambodia. Resistance is characterized by …
[图书][B] The selection and use of essential medicines: report of the WHO Expert Committee, 2015 (including the 19th WHO Model List of Essential Medicines and the 5th …
Organisation mondiale de la santé. Comité d'experts … - 2015 - books.google.com
This report presents the recommendations of the WHO Expert Committee responsible for
updating the WHO Model Lists of Essential Medicines.. The goal of the meeting was to …
updating the WHO Model Lists of Essential Medicines.. The goal of the meeting was to …
Antimalarial chemoprophylaxis for forest goers in southeast Asia: an open-label, individually randomised controlled trial
R Tripura, L von Seidlein, S Sovannaroth… - The Lancet Infectious …, 2023 - thelancet.com
Background Malaria in the eastern Greater Mekong subregion has declined to historic lows.
Countries in the Greater Mekong subregion are accelerating malaria elimination in the …
Countries in the Greater Mekong subregion are accelerating malaria elimination in the …