Genetic insights into the neurodevelopmental origins of schizophrenia
R Birnbaum, DR Weinberger - Nature Reviews Neuroscience, 2017 - nature.com
Schizophrenia is a severe neuropsychiatric disorder with a longstanding history of
neurobiological investigation. Although the underlying causal mechanisms remain …
neurobiological investigation. Although the underlying causal mechanisms remain …
The role of the immune system in autism spectrum disorder
A Meltzer, J Van de Water - Neuropsychopharmacology, 2017 - nature.com
Autism is a neurodevelopmental disorder characterized by deficits in communication and
social skills as well as repetitive and stereotypical behaviors. While much effort has focused …
social skills as well as repetitive and stereotypical behaviors. While much effort has focused …
Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder
INTRODUCTION Our understanding of the pathophysiology of psychiatric disorders,
including autism spectrum disorder (ASD), schizophrenia (SCZ), and bipolar disorder (BD) …
including autism spectrum disorder (ASD), schizophrenia (SCZ), and bipolar disorder (BD) …
What genes are differentially expressed in individuals with schizophrenia? A systematic review
AK Merikangas, M Shelly, A Knighton, N Kotler… - Molecular …, 2022 - nature.com
Schizophrenia is a severe, complex mental disorder characterized by a combination of
positive symptoms, negative symptoms, and impaired cognitive function. Schizophrenia is …
positive symptoms, negative symptoms, and impaired cognitive function. Schizophrenia is …
Pleiotropy and cross-disorder genetics among psychiatric disorders
Genome-wide analyses of common and rare genetic variations have documented the
heritability of major psychiatric disorders, established their highly polygenic genetic …
heritability of major psychiatric disorders, established their highly polygenic genetic …
Recent advances in the genetics of schizophrenia
D Avramopoulos - Complex Psychiatry, 2018 - karger.com
The last decade brought tremendous progress in the field of schizophrenia genetics. As a
result of extensive collaborations and multiple technological advances, we now recognize …
result of extensive collaborations and multiple technological advances, we now recognize …
Commonality in dysregulated expression of gene sets in cortical brains of individuals with autism, schizophrenia, and bipolar disorder
Individuals affected with different neuropsychiatric disorders such as autism (AUT),
schizophrenia (SCZ) and bipolar disorder (BPD), may share similar clinical manifestations …
schizophrenia (SCZ) and bipolar disorder (BPD), may share similar clinical manifestations …
Decreased brain pH as a shared endophenotype of psychiatric disorders
Although the brains of patients with schizophrenia and bipolar disorder exhibit decreased
brain pH relative to those of healthy controls upon postmortem examination, it remains …
brain pH relative to those of healthy controls upon postmortem examination, it remains …
The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease
S Bandres‐Ciga, S Saez‐Atienzar… - Movement …, 2019 - Wiley Online Library
Background PD is a complex polygenic disorder. In recent years, several genes from the
endocytic membrane‐trafficking pathway have been suggested to contribute to disease …
endocytic membrane‐trafficking pathway have been suggested to contribute to disease …
The Long Non-Coding RNA GOMAFU in Schizophrenia: Function, Disease Risk, and Beyond
PM Zakutansky, Y Feng - Cells, 2022 - mdpi.com
Neuropsychiatric diseases are among the most common brain developmental disorders,
represented by schizophrenia (SZ). The complex multifactorial etiology of SZ remains poorly …
represented by schizophrenia (SZ). The complex multifactorial etiology of SZ remains poorly …