Demethylating agent, 5-azacytidine, reverses differentiation of embryonic stem cells

K Tsuji-Takayama, T Inoue, Y Ijiri, T Otani… - Biochemical and …, 2004 - Elsevier
The de novo methylation activity is essential for embryonic development as well as
embryonic stem (ES) cell differentiation, where the intensive and extensive DNA methylation …

Hematopoietic differentiation of embryonic stem cells

I Orlovskaya, I Schraufstatter, J Loring, S Khaldoyanidi - Methods, 2008 - Elsevier
This review is focused on methods that are used to derive hematopoietic cells from
embryonic stem cells (ESCs). One of the strategies that have been recently used to achieve …

Effect of leukemia inhibitory factor on embryonic stem cell differentiation: implications for supporting neuronal differentiation

Z He, J Li, C Zhen, L Feng, X Ding - Acta Pharmacologica Sinica, 2006 - nature.com
Aim: Leukemia inhibitory factor (LIF), a pleiotropic cytokine, has been used extensively in the
maintenance of mouse embryonic stem cell pluripotency. In this current work, we examined …

Targeted deletion of Nm23/nucleoside diphosphate kinase A and B reveals their requirement for definitive erythropoiesis in the mouse embryo

EH Postel, I Wohlman, X Zou, T Juan… - … dynamics: an official …, 2009 - Wiley Online Library
The ubiquitously expressed nucleoside diphosphate kinases (Nm23/NDPK/Awd) are a large
family of multifunctional enzymes implicated in nucleic acid metabolism and in normal and …

[HTML][HTML] Erythropoietin induces sustained phosphorylation of STAT5 in primitive but not definitive erythrocytes generated from mouse embryonic stem cells

K Tsuji-Takayama, T Otani, T Inoue, S Nakamura… - Experimental …, 2006 - Elsevier
OBJECTIVE: During embryonic development murine erythropoiesis occurs in two waves by
producing first primitive erythroid cells (EryPs) and then definitive erythroid cells (EryDs) …

[HTML][HTML] Progenitor analysis of primitive erythropoiesis generated from in vitro culture of embryonic stem cells

T Otani, T Inoue, K Tsuji-Takayama, Y Ijiri… - Experimental …, 2005 - Elsevier
OBJECTIVE: A variety of hematopoietic lineage cells have been produced from embryonic
stem (ES) cells, but their differentiation processes have not been elucidated well, especially …

JAK2/STAT5 signaling pathway mediates Bojungbangdocktang enhanced hematopoiesis

J Lim, SJ Jeong, W Koh, I Han, HJ Lee… - Phytotherapy …, 2011 - Wiley Online Library
Bojungbangdocktang (BJBDT) is a medicinal herbal cocktail that has been used for cancer
prevention and treatment in traditional Korean medicine. In the current study, BJBDT was …

Modeling murine yolk sac hematopoiesis with embryonic stem cell culture systems

BD Cook - Frontiers in biology, 2014 - Springer
The onset of hematopoiesis in mammals is defined by generation of primitive erythrocytes
and macrophage progenitors in embryonic yolk sac. Laboratories have met the challenge of …

Potent anti-tumor killing activity of the multifunctional Treg cell line HOZOT against human tumors with diverse origins

T Inoue, Y Tashiro, M Takeuchi… - International …, 2011 - spandidos-publications.com
The T cell line HOZOT has a unique FOXP3+ CD4+ CD8+ CD25+ phenotype, exhibits
suppressive activity in allogeneic mixed lymphocyte reactions (MLR), and produces IL-10 …

Menstrual Blood Derived Angiogenesis Stimulatory Cells

F Lin, F Li, D Zhang, TE Ichim - US Patent App. 16/282,316, 2019 - Google Patents
Disclosed are angiogenesis stimulatory mesenchymal-like cells derived from menstrual
blood, originating from endo metrium and expressing increased levels of the protein CD39 …