Protein S‐palmitoylation (hereinafter referred to as protein palmitoylation) is a reversible
lipid posttranslational modification catalyzed by the zinc finger DHHC‐type containing …

The metabolism of glucose and lipids is essential for energy production in the body, and
dysregulation of the metabolic pathways of these molecules is implicated in various acute …

With a limited number of genes, cells achieve remarkable diversity. This is to a large extent
achieved by chemical posttranslational modifications of proteins. Amongst these are the lipid …

Palmitic acid (PA) is a saturated fatty acid commonly found in coconut oil and palm oil. It
serves as an energy source for the body and plays a role in the structure and function of cell …

The therapies targeting mutations of driver genes in cancer have advanced into clinical trials
for a variety of tumors. In glioblastoma (GBM), epidermal growth factor receptor (EGFR) is …

Posttranslational modifications increase the complexity and functional diversity of proteins in
response to complex external stimuli and internal changes. Among these, protein lipidations …

Background Excessive osteoclast formation disrupts bone homeostasis, thereby significantly
contributing to pathological bone loss associated with a variety of diseases. Protein S …

Immune evasion contributes to cancer growth and progression. Cancer cells have the ability
to activate different immune checkpoint pathways that harbor immunosuppressive functions …

Post-translational modifications of proteins in malignant transformation and tumor
maintenance of pancreatic ductal adenocarcinoma (PDAC) in the context of KRAS signaling …

Binding of CD95, a cell surface death receptor, to its homologous ligand CD95L, transduces
a cascade of downstream signals leading to apoptosis crucial for immune homeostasis and …