HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes

S Gupta, S Nerli, S Kutti Kandy, GL Mersky… - Nature …, 2023 - nature.com
The class I proteins of the major histocompatibility complex (MHC-I) display epitopic
peptides derived from endogenous proteins on the cell surface for immune surveillance …

Conformational plasticity of RAS Q61 family of neoepitopes results in distinct features for targeted recognition

AC McShan, D Flores-Solis, Y Sun, SE Garfinkle… - Nature …, 2023 - nature.com
The conformational landscapes of peptide/human leucocyte antigen (pHLA) protein
complexes encompassing tumor neoantigens provide a rationale for target selection …

A structure-guided approach to predict MHC-I restriction of T cell receptors for public antigens

S Gupta, N Sgourakis - bioRxiv, 2024 - biorxiv.org
Peptides presented by class I major histocompatibility complex (MHC-I) proteins provide
biomarkers for therapeutic targeting using T cell receptors (TCRs), TCR-mimicking …