[HTML][HTML] Cardiac transmembrane ion channels and action potentials: cellular physiology and arrhythmogenic behavior

V András, J Tomek, N Nagy, L Virág… - Physiological …, 2021 - journals.physiology.org
Cardiac arrhythmias are among the leading causes of mortality. They often arise from
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …

G-protein–coupled receptors in heart disease

J Wang, C Gareri, HA Rockman - Circulation research, 2018 - Am Heart Assoc
GPCRs (G-protein [guanine nucleotide-binding protein]–coupled receptors) play a central
physiological role in the regulation of cardiac function in both health and disease and thus …

[图书][B] Miller's anesthesia, 2-volume set E-book

MA Gropper, LI Eriksson, LA Fleisher… - 2019 - books.google.com
Covering everything from historical and international perspectives to basic science and
current clinical practice, Miller's Anesthesia, 9th Edition, remains the preeminent reference in …

Modernized classification of cardiac antiarrhythmic drugs

M Lei, L Wu, DA Terrar, CLH Huang - Circulation, 2018 - Am Heart Assoc
Background: Among his major cardiac electrophysiological contributions, Miles Vaughan
Williams (1918–2016) provided a classification of antiarrhythmic drugs that remains central …

SARS-CoV-2 infection induces ferroptosis of sinoatrial node pacemaker cells

Y Han, J Zhu, L Yang, BE Nilsson-Payant… - Circulation …, 2022 - Am Heart Assoc
Background: Increasing evidence suggests that cardiac arrhythmias are frequent clinical
features of coronavirus disease 2019 (COVID-19). Sinus node damage may lead to …

Gene editing to prevent ventricular arrhythmias associated with cardiomyocyte cell therapy

S Marchiano, K Nakamura, H Reinecke, L Neidig… - Cell Stem Cell, 2023 - cell.com
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) offer a promising cell-
based therapy for myocardial infarction. However, the presence of transitory ventricular …

Role of the autonomic nervous system in atrial fibrillation: pathophysiology and therapy

PS Chen, LS Chen, MC Fishbein, SF Lin… - Circulation …, 2014 - Am Heart Assoc
Autonomic nervous system activation can induce significant and heterogeneous changes of
atrial electrophysiology and induce atrial tachyarrhythmias, including atrial tachycardia and …

Gender differences in the effects of cardiovascular drugs

J Tamargo, G Rosano, T Walther… - European Heart …, 2017 - academic.oup.com
An initiation-promotion protocol was used to test the hypothesis that unleaded gasoline (UG)
vapor acts as a liver tumor promoter in female mice under exposure conditions in which UG …

[HTML][HTML] hERG K+ channels: structure, function, and clinical significance

JI Vandenberg, MD Perry, MJ Perrin… - Physiological …, 2012 - journals.physiology.org
The human ether-a-go-go related gene (hERG) encodes the pore-forming subunit of the
rapid component of the delayed rectifier K+ channel, Kv11. 1, which are expressed in the …

[HTML][HTML] Vascular endothelial dysfunction and pharmacological treatment

JB Su - World journal of cardiology, 2015 - ncbi.nlm.nih.gov
The endothelium exerts multiple actions involving regulation of vascular permeability and
tone, coagulation and fibrinolysis, inflammatory and immunological reactions and cell …