Ribonucleoprotein (RNP) granules are diverse membrane-less organelles that form through
multivalent RNA-RNA, RNA-protein, and protein-protein interactions between RNPs. RNP …

Eukaryotic cells are segmented into multiple compartments or organelles within the cell that
regulate distinct chemical and biological processes. Membrane-less organelles are …

RNA granules are dynamic entities controlling the spatiotemporal distribution and translation
of RNA molecules. In neurons, a variety of RNA granules exist both in the soma and in …

DEAD-and DExH-box ATPases (DDX/DHXs) are abundant and highly conserved cellular
enzymes ubiquitously involved in RNA processing. By remodeling RNA–RNA and RNA …

DEAD-box helicases are global regulators of liquid-liquid phase separation (LLPS), a
process that assembles membraneless organelles inside cells. An outstanding member of …

RNA helicases—central enzymes in RNA metabolism—often feature intrinsically disordered
regions (IDRs) that enable phase separation and complex molecular interactions. In the …

G-quadruplexes (G4s) have long been implicated in the regulation of chromatin packaging
and gene expression. These processes require or are accelerated by the separation of …

Background Liver ischemia/reperfusion (I/R) injury is usually caused by hepatic inflow
occlusion during liver surgery, and is frequently observed during war wounds and trauma …

Ribosome biogenesis is coordinated within the nucleolus, a biomolecular condensate that
exhibits dynamic material properties that are thought to be important for nucleolar function …

As positive-sense RNA viruses, the genomes of flaviviruses serve as the template for all
stages of the viral life cycle, including translation, replication, and infectious particle …