The loss of control over drug intake that occurs in addiction was initially believed to result
from disruption of subcortical reward circuits. However, imaging studies in addictive …

The obesity epidemic has been widely publicized in the media worldwide. Investigators at all
levels have been looking for factors that have contributed to the development of this …

Substance use disorder (SUD) is characterized, in part by behavior biased toward drug use
and away from natural sources of reward (eg, social interaction, food, sex). The …

BACKGROUND: Individuals with cocaine use disorder (CUD) chose cocaine over nondrug
rewards. In two newly designed laboratory tasks with pictures, we document this modified …

Rationale Addiction theories posit that drug-related cues maintain and contribute to drug use
and relapse. Indeed, our recent study in cocaine-dependent patients demonstrated that …

Aerobic exercise may represent a useful intervention for drug abuse in predisposed
individuals. Exercise increases plasticity in the brain that could be used to reverse learned …

The functional significance of newly formed granule neurons in the adult mammalian
hippocampus remains a mystery. Recently, it was demonstrated that wheel running …

Background: Recently, a simple procedure in mice, Drinking‐in‐the‐Dark (DID), was
hypothesized to have value for medication development for human alcoholism. In DID, mice …

La definición de adicción propuesta por la Organización Mundial de la Salud, dicha de
manera sucinta, indica que es una enfermedad cerebral que provoca una búsqueda …

Because of its primary role in drug‐seeking, consumption and addictive behaviour, there is a
growing interest in identifying the neural circuits and molecular mechanisms underlying the …