Osteoporosis is a common skeletal disease, affecting~ 200 million people around the world.
As a complex disease, osteoporosis is influenced by many factors, including diet (eg calcium …

Bone mass is a key determinant of osteoporosis and fragility fractures. Epidemiologic
studies have shown that a 10% increase in peak bone mass (PBM) at the population level …

Excess adiposity in childhood may affect bone development, ultimately leading to bone
frailty. Previous reports showing an increased rate of extremity fractures in children with …

Body weight impacts both bone turnover and bone density, making it, therefore, an important
risk factor for vertebral and hip fractures and ranking it alongside age in importance. The …

Context: Increased body fat is a risk factor for cardiovascular and metabolic disease, yet it is
uncertain whether obesity protects against osteoporosis or adiposity is harmful to bone …

With the rise in obesity worldwide, an important debate has developed as to whether excess
fat has a detrimental or protective effect on skeletal health in children and adults. Obese …

Context: Although muscle mass is beneficial to bone, studies on the effect of fat mass on
bone have yielded conflicting results. Objective: The aim of this study was to assess the …

Osteoporosis and obesity are both major public health concerns. It has long been
considered that these are distinct disorders rarely found in the same individual; however …

Loss of body weight is associated with bone loss, and body weight gain is associated with
increased bone formation. The molecular mechanisms linking body weight, body …

Background: Whereas excess adiposity is presumed to be advantageous for the skeleton,
studies investigating relations between bone strength and fat during youth have been …