Adverse cardiovascular effects and potential molecular mechanisms of DEHP and its metabolites—a review

ZJ Wen, ZY Wang, YF Zhang - Science of The Total Environment, 2022 - Elsevier
Currently, cardiovascular disease (CVD) is a health hazard that is associated with
progressive deterioration upon exposure to environmental pollutants. Di (2-ethylhexyl) …

Phthalates implications in the cardiovascular system

M Mariana, E Cairrao - Journal of cardiovascular development and …, 2020 - mdpi.com
Today's sedentary lifestyle and eating habits have been implicated as some of the causes of
the increased incidence of several diseases, including cancer and cardiovascular diseases …

Bisphenols and phthalates: Plastic chemical exposures can contribute to adverse cardiovascular health outcomes

M Ramadan, B Cooper, NG Posnack - Birth defects research, 2020 - Wiley Online Library
Phthalates and bisphenols are high production volume chemicals that are used in the
manufacturing of consumer and medical products. Given the ubiquity of bisphenol and …

Phthalate metabolites in breast milk from mothers in Southern China: Occurrence, temporal trends, daily intake, and risk assessment

Y Liu, M Xiao, K Huang, J Cui, H Liu, Y Yu, S Ma… - Journal of Hazardous …, 2024 - Elsevier
The extensive production and use of phthalates means that these compounds are now
ubiquitous in the environment and various biota, which raises concerns about potential …

Mechanistic insight into toxicity of phthalates, the involved receptors, and the role of Nrf2, NF-κB, and PI3K/AKT signaling pathways

H Mohammadi, S Ashari - Environmental Science and Pollution Research, 2021 - Springer
The wide use of phthalates, as phthalates are used in the manufacturing of not only plastics
but also many others goods, has become a main concern in the current century because of …

[HTML][HTML] Gestational exposure to perfluoroalkyl substances and congenital heart defects: a nested case-control pilot study

Y Ou, X Zeng, S Lin, MS Bloom, F Han, X Xiao… - Environment …, 2021 - Elsevier
Background Accumulating evidence suggests that environmental pollutants may contribute
to the occurrence of congenital heart defects (CHDs). However, no previous studies have …

[HTML][HTML] Acetylation of H3K4, H3K9, and H3K27 mediated by p300 regulates the expression of GATA4 in cardiocytes

W Zhou, D Jiang, J Tian, L Liu, T Lu, X Huang, H Sun - Genes & Diseases, 2019 - Elsevier
GATA4 is a particularly important cardiogenic transcription factor and serves as a potent
driver of cardiogenesis. Recent progress in the field has made it clear that histone …

Impacts of environmental insults on cardiovascular aging

Y Lan, S Wu - Current environmental health reports, 2022 - Springer
Abstract Purpose of Review With cardiovascular disease (CVD) being the top cause of
deaths worldwide, it is important to ensure healthy cardiovascular aging through enhanced …

Prenatal exposure to corn oil, CMC-Na or DMSO affects physical development and multi-organ functions in fetal mice

K Chen, X Lu, D Xu, Y Guo, Y Ao, H Wang - Reproductive Toxicology, 2023 - Elsevier
Corn oil, sodium carboxymethyl cellulose (CMC-Na), and dimethyl sulfoxide (DMSO) are
widely used as solvents or suspensions in animal experiments, but the effects of prenatal …

Developmental toxicant exposures and sex-specific effects on epigenetic programming and cardiovascular health across generations

LK Svoboda, T Ishikawa… - Environmental epigenetics, 2022 - academic.oup.com
Despite substantial strides in diagnosis and treatment, cardiovascular diseases (CVDs)
continue to represent the leading cause of death in the USA and around the world, resulting …