Oleanolic acid: extraction, characterization and biological activity

JM Castellano, S Ramos-Romero, JS Perona - Nutrients, 2022 - mdpi.com
Oleanolic acid, a pentacyclic triterpenoid ubiquitously present in the plant kingdom, is
receiving outstanding attention from the scientific community due to its biological activity …

Immunomodulatory properties of triterpenes

G Renda, İ Gökkaya, D Şöhretoğlu - Phytochemistry Reviews, 2022 - Springer
The immune system is one of the main defence mechanisms of the human body.
Inadequacy of this system or immunodeficiency results in increased risk of infections and …

[HTML][HTML] Metaflammation in glucolipid metabolic disorders: Pathogenesis and treatment

P Xiong, F Zhang, F Liu, J Zhao, X Huang, D Luo… - Biomedicine & …, 2023 - Elsevier
The public health issue of glucolipid metabolic disorders (GLMD) has grown significantly,
posing a grave threat to human wellness. Its prevalence is rising yearly and tends to affect …

Antiinflammatory activity of natural triterpenes—An overview from 2006 to 2021

RS Miranda, BSM de Jesus… - Phytotherapy …, 2022 - Wiley Online Library
Terpenes are one of the most abundant classes of secondary metabolites produced by
plants and can be divided based on the number of isoprene units (C5) in monoterpenes (2 …

Recent advances regarding the molecular mechanisms of triterpenic acids: A review (part I)

M Mioc, A Milan, D Malița, A Mioc, A Prodea… - International Journal of …, 2022 - mdpi.com
Triterpenic acids are phytocompounds with a widespread range of biological activities that
have been the subject of numerous in vitro and in vivo studies. However, their underlying …

Oleanolic acid alleviates atopic dermatitis-like responses in vivo and in vitro

YM Kang, HM Kim, M Lee, HJ An - International journal of molecular …, 2021 - mdpi.com
Oleanolic acid (OA) is a pentacyclic triterpenoid, abundantly found in plants of the Oleaceae
family, and is well known for its beneficial pharmacological activities. Previously, we …

Oleanolic acid alleviates cerebral ischemia/reperfusion injury via regulation of the GSK-3β/HO-1 signaling pathway

K Lin, Z Zhang, Z Zhang, P Zhu, X Jiang, Y Wang… - Pharmaceuticals, 2021 - mdpi.com
Oleanolic acid (OA), a bioactive ingredient of Panax ginseng, exhibits neuroprotective
pharmacological effects. However, the protective role of OA in cerebral ischemia and …

The in vitro and in vivo study of oleanolic acid indole derivatives as novel anti-inflammatory agents: Synthesis, biological evaluation, and mechanistic analysis

J Jin, H He, X Zhang, R Wu, L Gan, D Li, Y Lu, P Wu… - Bioorganic …, 2021 - Elsevier
Oleanolic acid (OA) is a well-known natural product possessing many important
pharmacological activities; however, its weak bioactivities significantly restrict the potential …

Licochalcone A inhibits IgE-mediated allergic reaction through PLC/ERK/STAT3 pathway

J Shu, X Cui, X Liu, W Yu, W Zhang… - International Journal …, 2022 - journals.sagepub.com
Licochalcone (LicA) is a flavonoid commonly derived from the licorice plant that is reported
to have a variety of pharmacological activities. However, few studies have focused on its anti …

Marine-Derived Alternariol Monomethyl Ether Alleviates Ovalbumin-Induced Food Allergy by Suppressing MAPK and NF-κB Signaling Pathways of Mast Cells

Y Liu, ZB Zou, FD Gu, YF Lin, Y Li… - Journal of Agricultural …, 2024 - ACS Publications
The prevalence of food allergies has grown dramatically over the past decade. Recently,
studies have shown the potential of marine substances to alleviate food allergies. We …