Currently, no therapeutic options exist for castration-resistant prostate cancer (CRPC)
patients who have developed resistance to the second generation anti-androgen receptor …

Toward identifying a cancer-specific gene signature we applied surprisal analysis to the
RNAs expression behavior for a large cohort of breast, lung, ovarian, and prostate …

Perturbations of the circadian clock are linked to multiple diseases, including cancers.
Pharmacological activation of REV-ERB nuclear receptors, the core components of the …

Immunotherapy success in colorectal cancer is mainly limited to patients whose tumors
exhibit high microsatellite instability (MSI). However, there is variability in treatment …

The STAT3 is often dysregulated in genitourinary tumors. In prostate cancer, STAT3
activation correlates with Gleason score and pathological stage and modulates cancer stem …

In this study, we have characterized the role of annexin A1 (ANXA1) in the acquisition and
maintenance of stem-like/aggressive features in prostate cancer (PCa) cells comparing …

The Mediator complex is a transcriptional regulator interacting with transcription factors and
RNA‐polymerase‐II. Recently, we identified its subunit CDK19 to be specifically expressed …

OBJECTIVE. The objective of our study was to investigate associations between quantitative
image features of multiparametric MRI of the prostate and PTEN expression of peripheral …

Men who enter active surveillance because their biopsy exhibits only Gleason grade 3 (G3)
frequently have higher grade tumor missed by biopsy. Thus, biomarkers are needed that …

Prostate cancer is the most common cancer in men by way of diagnosis and a leading cause
of cancer-related deaths. Early detection and intervention remains key to its optimum clinical …