Background Cancer cell metabolism requires sustained pools of intracellular nicotinamide
adenine dinucleotide (NAD+) which is maintained by a balance of NAD+ hydrolase activity …

Prostate Cancer is a cancer that occurs in the prostate-a small walnut shaped gland in men.
This gland helps in the production of seminal fluid which is used to nourish and transport the …

To identify molecular features associated with clinico‐pathological parameters and
TMPRSS2‐ERG fusion status in prostate cancer, we employed MALDI mass spectrometric …

Accurate prognosis and prediction of response to therapy are essential for personalized
treatment of cancer. Even though many prognostic gene lists and predictors have been …

The p53 protein plays a passive and an active role in stem cells. The transcriptional activities
of p53 for cell-cycle arrest and DNA repair are largely turned off in stem cells, but there is …

Androgen receptor (AR) regulation pathways are essential for supporting the growth and
survival of prostate cancer cells. Recently, sub-populations of prostate cancer cells have …

Introduction Ovarian cancer (OC) is one of the most frequent gynecologic cancers among
women, and high-accuracy risk prediction techniques are essential to effectively select the …

Approximately half of prostate cancers (PCa) carry TMPRSS2-ERG translocations; however,
the clinical impact of this genomic alteration remains enigmatic. Expression of v-ets …

Objective: Lung cancer exhibits unpredictable recurrence in low-stage tumors and variable
responses to different therapeutic interventions. Predicting relapse in early-stage lung …

Recent studies in the field of cancer stem cells have revealed that the alterations in key gene
products involved in the epithelial–mesenchymal transition (EMT) program, altered …