TonB-dependent transporters (TBDTs) are bacterial outer membrane proteins that bind and
transport ferric chelates, called siderophores, as well as vitamin B12, nickel complexes, and …

Colicins are proteins produced by and toxic for some strains of Escherichia coli. They are
produced by strains of E. coli carrying a colicinogenic plasmid that bears the genetic …

Heterotrimeric guanine nucleotide–binding protein (G protein)–coupled receptors constitute
the largest family of eukaryotic signal transduction proteins that communicate across the …

The lipid cubic phase or in meso method is a robust approach for crystallizing membrane
proteins for structure determination. The uptake of the method is such that it is experiencing …

A detailed protocol for crystallizing membrane proteins that makes use of lipidic
mesophases is described. This has variously been referred to as the lipid cubic phase or in …

Membrane protein structural biology is still a largely unconquered area, given that
approximately 25% of all proteins are membrane proteins and yet less than 150 unique …

The outer membranes of Gram-negative bacteria, mitochondria, and chloroplasts all contain
transmembrane β-barrel proteins. These β-barrel proteins serve essential functions in cargo …

Membrane protein structures are stabilized by weak interactions and are influenced by
additional interactions with the solubilizing environment. Structures of influenza virus A M2 …

Bacteria are able to survive in low-iron environments by sequestering this metal ion from
iron-containing proteins and other biomolecules such as transferrin, lactoferrin, heme …

The principal route to determine the structure and the function and interactions of membrane
proteins is via macromolecular crystallography. For macromolecular crystallography to be …