Endothelial-to-mesenchymal transition is a dynamic process in which endothelial cells
suppress constituent endothelial properties and take on mesenchymal cell behaviors. To …

The complexity of morphogenesis poses a fundamental challenge to understanding the
mechanisms governing the formation of biological patterns and structures. Over the past …

Blood clotting is a finely regulated process that is essential for hemostasis. However, when
dysregulated or spontaneous, it promotes thrombotic disorders. The fact that these are …

Disruption in vascularization during wound repair can severely impair healing.
Proangiogenic growth factor therapies have shown great healing potential; however …

Tissue regeneration after injury requires coordinated regulation of stem cell activation,
division, and daughter cell differentiation, processes that are increasingly well understood in …

Mechanical forces are an inherent element in the world around us. The effects of their action
can be observed both on the macro and molecular levels. They can also play a prominent …

Activin A receptor like type 1 (ALK1) is a transmembrane serine/threonine receptor kinase in
the transforming growth factor-beta receptor family that is expressed on endothelial cells …

The HOXA9 transcription factor serves as a molecular orchestrator in cancer stemness,
epithelial-mesenchymal transition (EMT), metastasis, and generation of the tumor …

Fetal growth restriction (FGR), which most commonly results from suboptimal placental
function, substantially increases risks for adverse perinatal and long-term outcomes. The …

Doxorubicin (DOX) is an effective antineoplastic agent used to treat various types of cancers.
However, its use is limited by the development of cardiotoxicity, which may result in heart …