Pathophysiology of chronic limb ischemia
Die chronisch arterielle Ischämie der unteren Extremitäten stellt ein alltägliches Problem in
gefäßchirurgischen Kliniken dar. In Deutschland sind etwa 3% aller Hospitalisierungen auf …
gefäßchirurgischen Kliniken dar. In Deutschland sind etwa 3% aller Hospitalisierungen auf …
Acetyl-CoA carboxylase 1 regulates endothelial cell migration by shifting the phospholipid composition
DK Glatzel, A Koeberle, H Pein, K Löser, A Stark… - Journal of lipid …, 2018 - ASBMB
The enzyme acetyl-CoA carboxylase (ACC) plays a crucial role in fatty acid metabolism. In
recent years, ACC has been recognized as a promising drug target for treating different …
recent years, ACC has been recognized as a promising drug target for treating different …
A multiscale model of complex endothelial cell dynamics in early angiogenesis
We introduce a hybrid two-dimensional multiscale model of angiogenesis, the process by
which endothelial cells (ECs) migrate from a pre-existing vascular bed in response to local …
which endothelial cells (ECs) migrate from a pre-existing vascular bed in response to local …
Succinylated chitosan derivative restore HUVEC cells function damaged by TNF-α and high glucose in vitro and enhanced wound healing
Z Chen, M Yuan, H Li, L Li, B Luo, L Lu, Q Xiang… - International Journal of …, 2024 - Elsevier
The inflammation of chronic wounds plays a key hindering role in the wound healing
process. Slowing down the inflammatory response is significant for the repair of chronic …
process. Slowing down the inflammatory response is significant for the repair of chronic …
Unraveling Endothelial Cell Migration: Insights into Fundamental Forces, Inflammation, Biomaterial Applications, and Tissue Regeneration Strategies
D Jerka, K Bonowicz, K Piekarska… - ACS Applied Bio …, 2024 - ACS Publications
Cell migration is vital for many fundamental biological processes and human pathologies
throughout our life. Dynamic molecular changes in the tissue microenvironment determine …
throughout our life. Dynamic molecular changes in the tissue microenvironment determine …
Planar-polarized semaphorin-5c and plexin A promote the collective migration of epithelial cells in Drosophila
Collective migration of epithelial cells is essential for morphogenesis, wound repair, and the
spread of many cancers, yet how individual cells signal to one another to coordinate their …
spread of many cancers, yet how individual cells signal to one another to coordinate their …
Computational modeling of angiogenesis: The importance of cell rearrangements during vascular growth
Angiogenesis is the process wherein endothelial cells (ECs) form sprouts that elongate from
the pre‐existing vasculature to create new vascular networks. In addition to its essential role …
the pre‐existing vasculature to create new vascular networks. In addition to its essential role …
Junction-based lamellipodia drive endothelial cell rearrangements in vivo via a VE-cadherin-F-actin based oscillatory cell-cell interaction
Angiogenesis and vascular remodeling are driven by extensive endothelial cell movements.
Here, we present in vivo evidence that endothelial cell movements are associated with …
Here, we present in vivo evidence that endothelial cell movements are associated with …
Spatial-controlled coating of pro-angiogenic proteins on 3D porous hydrogels guides endothelial cell behavior
C Le Bao, H Waller, A Dellaquila, D Peters… - International Journal of …, 2022 - mdpi.com
In tissue engineering, the composition and the structural arrangement of molecular
components within the extracellular matrix (ECM) determine the physical and biochemical …
components within the extracellular matrix (ECM) determine the physical and biochemical …
Ex Vivo treatment of coronary artery endothelial cells with serum post-exercise training offers limited protection against in vitro exposure to FEC-T chemotherapy
M Mclaughlin, KL Hesketh, SL Horgan… - Frontiers in …, 2023 - frontiersin.org
Background: Chemotherapy treatment for breast cancer associates with well-documented
cardiovascular detriments. Exercise has shown promise as a potentially protective …
cardiovascular detriments. Exercise has shown promise as a potentially protective …