[HTML][HTML] Brusatol induces ferroptosis in oesophageal squamous cell carcinoma by repressing GSH synthesis and increasing the labile iron pool via inhibition of the …

X Zhu, N Huang, Y Ji, X Sheng, J Huo, Y Zhu… - Biomedicine & …, 2023 - Elsevier
Brusatol (Bru), a bioactive compound found in Brucea sumatrana, exerts antitumour effects
on several malignancies. However, the role and molecular mechanism of Bru in squamous …

[HTML][HTML] Suppression of metastatic organ colonization and antiangiogenic activity of the orally bioavailable lipid raft-targeted alkylphospholipid edelfosine

V Alonso-Pérez, V Hernández, MA Calzado… - Biomedicine & …, 2024 - Elsevier
Metastasis is the leading cause of cancer mortality. Metastatic cancer is notoriously difficult
to treat, and it accounts for the majority of cancer-related deaths. The ether lipid edelfosine is …