Morphological parameters able to predict BRAFV600E‐mutated malignancies on thyroid fine‐needle aspiration cytology: Our institutional experience

ED Rossi, T Bizzarro, M Martini… - Cancer …, 2014 - Wiley Online Library
BACKGROUND The BRAFV600E mutation is the most common diagnostic/prognostic
marker in papillary thyroid carcinoma (PTC). Its evaluation is typically performed with DNA …

[HTML][HTML] Detection of circulating BRAFV600E in patients with papillary thyroid carcinoma

CC Lubitz, S Parangi, TM Holm, MJ Bernasconi… - The Journal of Molecular …, 2016 - Elsevier
BRAF V600E is a common mutation in papillary thyroid carcinoma (PTC) correlated with
aggressive features. Our objective was to assess the feasibility and accuracy of a novel RNA …

[HTML][HTML] Tyrosine kinase inhibitors for radioactive iodine refractory differentiated thyroid cancer

C Cortas, H Charalambous - Life, 2023 - mdpi.com
Patients with differentiated thyroid cancer usually present with early-stage disease and
undergo surgery followed by adjuvant radioactive iodine ablation, resulting in excellent …

Comparison of droplet digital PCR and direct Sanger sequencing for the detection of the BRAFV600E mutation in papillary thyroid carcinoma

Z Wang, K Sun, C Jing, H Cao, R Ma… - Journal of Clinical …, 2019 - Wiley Online Library
Abstract Background The BRAFV600E mutation status is a useful diagnostic and prognostic
marker for papillary thyroid carcinoma (PTC). Although it is a commonly used method …

A prospective study evaluating the accuracy of using combined clinical factors and candidate diagnostic markers to refine the accuracy of thyroid fine needle …

A Mathur, J Weng, W Moses, SM Steinberg… - Surgery, 2010 - Elsevier
BACKGROUND: Approximately 30% of fine needle aspiration biopsies of the thyroid have
inconclusive results. We conducted a prospective trial to determine whether clinical and …

Pilot of BRAF mutation analysis in indeterminate, suspicious and malignant thyroid FNA cytology

SJ Johnson, SA Hardy, C Roberts, D Bourn… - …, 2014 - Wiley Online Library
Background BRAF V600E mutation has been reported to show a high specificity for papillary
thyroid carcinoma (PTC). Using this marker to upgrade 'indeterminate'or 'suspicious' thyroid …

BRAF analysis by fine needle aspiration biopsy of thyroid nodules improves preoperative identification of papillary thyroid carcinoma and represents a prognostic …

MR Pelizzo, IM Boschin, S Barollo… - Clinical chemistry and …, 2011 - degruyter.com
Background: The current preoperative diagnosis of a thyroid mass relies on microscopic
evaluation of thyroid cells obtained by fine needle aspiration biopsy (FNAB). More recently …

Applications and limitations of oncogene mutation testing in clinical cytopathology

C Bellevicine, G De Vita, U Malapelle… - Seminars in Diagnostic …, 2013 - Elsevier
In an increased number of settings, cytology represents the only source of sampling and it
often substitutes histology as an independent diagnostic modality. Thus, DNA molecular …

BRAF mutation analysis of fine-needle aspiration biopsies of papillary thyroid carcinoma: impact on diagnosis and prognosis

A Colanta, O Lin, L Tafe, R Ghossein, K Nafa… - Acta cytologica, 2011 - karger.com
Objective: The BRAF V600E mutation has been associated with aggressive disease in
papillary thyroid carcinoma (PTC). Molecular testing has been proposed as a useful adjunct …

Circulating BRAFV600E Levels Correlate with Treatment in Patients with Thyroid Carcinoma

CC Lubitz, T Zhan, V Gunda, S Amin, BJ Gigliotti… - Thyroid, 2018 - liebertpub.com
Background: BRAFV600E is the most common mutation in papillary thyroid carcinoma (PTC)
and can be associated with aggressive disease. Previously, a highly sensitive blood RNA …