Focus on your locus with a massively parallel reporter assay
A growing number of variants associated with risk for neurodevelopmental disorders have
been identified by genome-wide association and whole genome sequencing studies. As …
been identified by genome-wide association and whole genome sequencing studies. As …
[HTML][HTML] Trastornos del neurodesarrollo: dónde estamos hoy y hacia dónde nos dirigimos
I López, J Förster - Revista médica clínica las condes, 2022 - Elsevier
El término trastornos del neurodesarrollo agrupa a un conjunto amplio y heterogéneo de
condiciones de origen multifactorial, de inicio precoz en la vida, de curso crónico, altamente …
condiciones de origen multifactorial, de inicio precoz en la vida, de curso crónico, altamente …
The long non-coding RNA-ORLNC1 regulates bone mass by directing mesenchymal stem cell fate
L Yang, Y Li, R Gong, M Gao, C Feng, T Liu, Y Sun… - Molecular Therapy, 2019 - cell.com
Bone marrow-derived mesenchymal stem cells (BMSCs) have the potential to differentiate
into osteoblasts or adipocytes, and the shift between osteogenic and adipogenic …
into osteoblasts or adipocytes, and the shift between osteogenic and adipogenic …
De novo Mutations From Whole Exome Sequencing in Neurodevelopmental and Psychiatric Disorders: From Discovery to Application
Neurodevelopmental and psychiatric disorders are a highly disabling and heterogeneous
group of developmental and mental disorders, resulting from complex interactions of genetic …
group of developmental and mental disorders, resulting from complex interactions of genetic …
Dynamic variations of 3′ UTR length reprogram the mRNA regulatory landscape
E Navarro, A Mallén, M Hueso - Biomedicines, 2021 - mdpi.com
This paper concerns 3′-untranslated regions (3′ UTRs) of mRNAs, which are non-coding
regulatory platforms that control stability, fate and the correct spatiotemporal translation of …
regulatory platforms that control stability, fate and the correct spatiotemporal translation of …
Electroacupuncture promoted nerve repair after peripheral nerve injury by regulating miR-1b and its target brain-derived neurotrophic factor
YP Liu, Z Luo, C Wang, H Cai, T Zhao, H Li… - Frontiers in …, 2020 - frontiersin.org
Growing evidence indicates that electroacupuncture (EA) has a definite effect on the
treatment of peripheral nerve injury (PNI), but its mechanism is not completely clear …
treatment of peripheral nerve injury (PNI), but its mechanism is not completely clear …
Viruses as Living Systems—A Metacybernetic View
M Yolles, R Frieden - Systems, 2022 - mdpi.com
The debate over whether viruses are living organisms tends to be paradigmatically
determined. The metabolic paradigm denies that they are, while new research evidences …
determined. The metabolic paradigm denies that they are, while new research evidences …
Prenatal exposure to glufosinate ammonium disturbs gut microbiome and induces behavioral abnormalities in mice
T Dong, Q Guan, W Hu, M Zhang, Y Zhang… - Journal of hazardous …, 2020 - Elsevier
Glufosinate ammonium (GLA) is a widely used organophosphate herbicide, which could be
commonly detected in body fluids of both pregnant women and newborns. Existing …
commonly detected in body fluids of both pregnant women and newborns. Existing …
Choice of alternative polyadenylation sites, mediated by the RNA-binding protein Elavl3, plays a role in differentiation of inhibitory neuronal progenitors
E Grassi, R Santoro, A Umbach, A Grosso… - Frontiers in Cellular …, 2019 - frontiersin.org
Alternative polyadenylation (APA) is a widespread mechanism involving about half of the
expressed genes, resulting in varying lengths of the 3′ untranslated region (3′ UTR) …
expressed genes, resulting in varying lengths of the 3′ untranslated region (3′ UTR) …
DNA methyltransferase 1 is dysregulated in Parkinson's disease via mediation of miR-17
HQ Zhang, JY Wang, ZF Li, L Cui, SS Huang… - Molecular …, 2021 - Springer
Aberrant DNA methylation is closely associated with the pathogenesis of Parkinson's
disease (PD). DNA methyltransferases (DNMTs) are the enzymes for establishment and …
disease (PD). DNA methyltransferases (DNMTs) are the enzymes for establishment and …