Macrophages are influential members of the innate immune system that can be reversibly
polarized by different microenvironment signals. Cell polarization leads to a wide range of …

Pulmonary fibrosis (PF) is a feared component in over 200 interstitial pulmonary diseases,
which are characterized by increased alveolar wall thickness, excessive scarring, and …

Idiopathic pulmonary fibrosis is incurable, and its progression is difficult to control and thus
can lead to pulmonary deterioration. Pan-histone deacetylase inhibitors such as SAHA have …

Cardiac stromal cells (CSCs) are the main players in fibrosis. Dysmetabolic conditions
(metabolic syndrome—MetS, and type 2 diabetes mellitus—DM2) are strong pathogenetic …

Objective Inflammatory responses are associated with changes in tissue metabolism. Prior
studies find altered metabolomic profiles in both the synovial fluid (SF) and serum of …

Fibrosis and the associated decline in organ functionality lead to an almost 50% mortality
rate in developed countries. Multipotent mesenchymal stromal cells (MSC) were shown to …

Diabetes mellitus (DM) is a significant public health problem and is one of the most
challenging medical conditions worldwide. It is the severe complications that make this …

Host regulatory immune response is involved in the hepatic inflammatory process caused by
the hepatitis C virus (HCV). We aimed to determine if HCV clearance with direct-acting …

The authors have observed fibrolipomatous growths in avid shortboard surfers that develop
at the points on the chest wall of repetitive contact with the surfboard while prone paddling …

Mechanical stimuli are regulators not only in cells but also in the extracellular matrix activity,
with special reference to collagen bundles composition, amount and distribution. Collagen …