Kinins are proinflammatory peptides that mediate numerous vascular and pain responses to
tissue injury. Two pharmacologically distinct kinin receptor subtypes have been identified …

The kallikrein-kinin system is an endogenous metabolic cascade, triggering of which results
in the release of vasoactive kinins (bradykinin-related peptides). This complex system …

A literature review on kinin pharmacology that appeared in this journal in 1980 was based
on a systematic effort to define two receptor types for bradykinin-(BK b) related peptides, and …

Kinins are among the most potent autacoids involved in inflammatory, vascular and pain
processes. These short-lived peptides, including bradykinin, kallidin and T-kinin, are …

A stress-activated serine/threonine protein kinase, p38 mitogen-activated protein kinase
(p38 MAPK), belongs to the MAP kinase superfamily. Diverse extracellular stimuli, including …

Kinins are a family of peptides implicated in several pathophysiological events. Most of their
effects are likely mediated by the activation of two G‐protein‐coupled receptors: B1 and B2 …

Many known painkillers are not always effective in the therapy of chronic neuropathic pain
manifested by hyperalgesia and tactile allodynia. The mechanisms underlying neuropathic …

The molecular mechanisms behind phenotypic modulation of smooth muscle cells (SMCs)
remain unclear. In our recent paper, we reported the establishment of novel culture system …

Bradykinin (BK) is a potent short-lived effector belonging to a class of peptides known as
kinins. It participates in inflammatory and vascular regulation and processes including …

Introduction: Kinins are peptide mediators exerting their pro-inflammatory actions by the
selective stimulation of two distinct G-protein coupled receptors, termed BKB1R and BKB2R …