[HTML][HTML] The emerging role of circular RNAs in cisplatin resistance in ovarian cancer: From Molecular mechanism to future potential

MM Mohammadi, H Rismanchi, A Farahani… - Non-coding RNA …, 2024 - Elsevier
Ovarian cancer (OC) is the most common cause of death in female cancers. The prognosis
of OC is very poor due to delayed diagnosis and identification of most patients in advanced …

Deregulated circRNAs in Epithelial Ovarian Cancer With Activity in Preclinical In Vivo Models: Identification of Targets and New Modalities for Therapeutic Intervention

UH Weidle, F Birzele - Cancer Genomics & Proteomics, 2024 - cgp.iiarjournals.org
Epithelial ovarian cancer (EOC) is associated with a dismal prognosis due to development
of resistance to chemotherapy and metastasis in the peritoneal cavity and distant organs. In …

Inorganic pyrophosphatase 1 activates the phosphatidylinositol 3-kinase/Akt signaling to promote tumorigenicity and stemness properties in colorectal cancer

T Niu, J Zhu, L Dong, P Yuan, L Zhang, D Liu - Cellular Signalling, 2023 - Elsevier
Colorectal cancer (CRC) is a common malignant tumor of the human digestive tract.
Inorganic pyrophosphatase 1 (PPA1) plays an imperative role in the advancement of …

Molecular Insights into the Breast and Prostate Cancer Cells in Response to the Change of Extracellular Zinc

SK Barman, MK Sen, DA Mahns, MJ Wu… - Journal of …, 2024 - Wiley Online Library
Zinc dyshomeostasis is manifested in breast and prostate cancer cells. This study attempted
to uncover the molecular details prodded by the change of extracellular zinc by employing a …

Structural and biochemical characterization of active sites mutant in human inorganic pyrophosphatase

S Zheng, C Zheng, S Chen, J Guo, L Huang… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Inorganic pyrophosphatases (PPases) are enzymes that catalyze the conversion of
inorganic pyrophosphate (PPi) into phosphate (Pi). Human inorganic pyrophosphatase 1 …

PPA1 Deficiency Causes a Deranged Galactose Metabolism Recognizable in Neonatal Screening

MT Achleitner, JJM Jans, L Ebner, J Spenger… - Metabolites, 2023 - mdpi.com
Two siblings showed increased galactose and galactose-related metabolites in neonatal
screening. Diagnostic workup did not reveal abnormalities in any of the known disease …

Molecular insights into the zinc homeostasis of breast and prostate cancer cells

SK Barman - 2023 - researchdirect.westernsydney.edu …
Abstract Zinc ion (Zn2+) is essential to life as a structural or catalytic component of proteins.
The cell has developed an elaborate molecular network over the extensive evolutionary …