The feasibility of polypill for cardiovascular disease prevention in Asian Population

A Sukonthasarn, YC Chia, JG Wang… - The Journal of …, 2021 - Wiley Online Library
Polypill is a fixed‐dose combination of medications with proven benefits for the prevention of
cardiovascular disease (CVD). Its role in CVD prevention has been extensively debated …

[HTML][HTML] Choice of drug therapy in primary (essential) hypertension

J Mann - Published online, 2020 - medilib.ir
INTRODUCTION—The global prevalence of hypertension is high, and among nonpregnant
adults in the United States, treatment of hypertension is the most common reason for office …

Harnessing CURATE. AI for N‐of‐1 Optimization Analysis of Combination Therapy in Hypertension Patients: A Retrospective Case Series

ATL Truong, LWJ Tan, KA Chew… - Advanced …, 2021 - Wiley Online Library
Hypertension is a global public health challenge that imposes a significant burden on
patients and healthcare systems. Conventional treatment involves dose escalation of an …

Analytical eco‐scale and quality by design‐oriented liquid chromatography method for simultaneous quantification of metoprolol succinate, telmisartan, and cilnidipine …

SS Panda, S Dutta, RKVV Bera… - Separation Science …, 2021 - Wiley Online Library
A new combination of metoprolol succinate, telmisartan, and cilnidipine is recently approved
to treat hypertension effectively. A reversed‐phase liquid chromatography method was …

Hinokitiol produces vasodilation in aortae from normal and angiotensin II-induced hypertensive rats via endothelial-dependent and independent pathways

AIA Laban, HM El-Bassossy, NA Hassan - Vascular Pharmacology, 2022 - Elsevier
Hinokitiol is a natural bioactive compound with numerous pharmacological properties. Here,
we aimed to examine hinokitiol's effects on vascular relaxation. Cumulative relaxation …

Adding a new medication versus maximizing dose to intensify hypertension treatment in older adults: a retrospective observational study

CE Aubert, JB Sussman, TP Hofer… - Annals of internal …, 2021 - acpjournals.org
Background: There are 2 approaches to intensifying antihypertensive treatment when target
blood pressure is not reached, adding a new medication and maximizing dose. Which …

Pathophysiological mechanisms underlying a rat model of triple whammy acute kidney injury

L Prieto-García, L Vicente-Vicente… - Laboratory …, 2020 - nature.com
Simultaneous administration of certain antihypertensive (renin–angiotensin system
inhibitors and diuretics) and nonsteroidal anti-inflammatory drugs (NSAIDs) is associated …

P2B001 (extended release pramipexole and rasagiline): a new treatment option in development for Parkinson's disease

RA Hauser, N Giladi, W Poewe, J Brotchie… - Advances in …, 2022 - Springer
Despite levodopa's superior efficacy in reducing the motor symptoms of Parkinson's disease
(PD), its risk to induce motor complications requires consideration of the pros and cons of …

[PDF][PDF] 抗肿瘤药物相关高血压的研究进展

夏云龙, 刘飞 - 临床心血管病杂志, 2022 - lcxxgen.whuhzzs.com
癌症是全世界死亡的主要原因之一, 不断演进的抗癌药物使癌症患者的生存期明显延长.
心血管疾病逐步取代癌症本身成为癌症患者致死和致残的主要原因, 高血压是其中最常见的心 …

Современная антигипертензивная терапия: возможности уникальной российской фиксированной комбинации рамиприла и индапамида

АО Конради, СВ Недогода… - Российский …, 2020 - cyberleninka.ru
Артериальная гипертензия (АГ), несмотря на име‑ющиеся достижения в борьбе с ней,
является одним из самых распространенных сердечно‑сосудистых заболеваний (ССЗ) …