Post-acute sequelae of COVID-19: understanding and addressing the burden of multisystem manifestations

M Parotto, M Gyöngyösi, K Howe, SN Myatra… - The Lancet …, 2023 - thelancet.com
Individuals with SARS-CoV-2 infection can develop symptoms that persist well beyond the
acute phase of COVID-19 or emerge after the acute phase, lasting for weeks or months after …

COVID-19 complications: oxidative stress, inflammation, and mitochondrial and endothelial dysfunction

E Georgieva, J Ananiev, Y Yovchev… - International Journal of …, 2023 - mdpi.com
SARS-CoV-2 infection, discovered and isolated in Wuhan City, Hubei Province, China,
causes acute atypical respiratory symptoms and has led to profound changes in our lives …

COVID-19 causes ferroptosis and oxidative stress in human endothelial cells

SS Jankauskas, U Kansakar, C Sardu, F Varzideh… - Antioxidants, 2023 - mdpi.com
Oxidative stress and endothelial dysfunction have been shown to play crucial roles in the
pathophysiology of COVID-19 (coronavirus disease 2019). On these grounds, we sought to …

SARS-CoV-2 and the spike protein in endotheliopathy

L Perico, A Benigni, G Remuzzi - Trends in Microbiology, 2024 - cell.com
Abstract SARS-CoV-2, the causative agent of COVID-19, primarily affects the epithelial
compartment in the upper and lower airways. There is evidence that the microvasculature in …

Cognitive dysfunction in post‐COVID‐19 condition: Mechanisms, management, and rehabilitation

M Möller, K Borg, C Janson, M Lerm… - Journal of Internal …, 2023 - Wiley Online Library
The long‐term effects of COVID‐19 on cognitive function have become an area of increasing
concern. This paper provides an overview of characteristics, risk factors, possible …

Prognostic value of von Willebrand factor and ADAMTS13 in patients with COVID-19: A systematic review and meta-analysis

X Xu, Y Feng, Y Jia, X Zhang, L Li, X Bai, L Jiao - Thrombosis Research, 2022 - Elsevier
Background Endotheliopathy and coagulopathy appear to be the main causes for critical
illness and death in patients with coronavirus disease 2019 (COVID-19). The adhesive …

Biological assessment of the NO-dependent endothelial function

H Boughaleb, I Lobysheva, F Dei Zotti, JL Balligand… - Molecules, 2022 - mdpi.com
Nitric oxide (NO) is implicated in numerous physiological processes, including vascular
homeostasis. Reduced NO bioavailability is a hallmark of endothelial dysfunction, a prequel …

Single-cell transcriptomics reveals evidence of endothelial dysfunction in the brains of COVID-19 patients with implications for glioblastoma progression

A Thakur, L Liang, S Banerjee, K Zhang - Brain sciences, 2023 - mdpi.com
Background: Endothelial dysfunction is implicated in various inflammatory diseases such as
ischemic stroke, heart attack, organ failure, and COVID-19. Recent studies have shown that …

Facing the challenges in the COVID-19 pandemic era: from standard treatments to the umbilical cord-derived mesenchymal stromal cells as a new therapeutic strategy

E Russo, S Corrao, F Di Gaudio, G Alberti, M Caprnda… - Cells, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19), the pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), which counts more than 650 million cases and …

Unbalanced IDO1/IDO2 endothelial expression and skewed keynurenine pathway in the pathogenesis of COVID-19 and Post-COVID-19 pneumonia

M Chilosi, C Doglioni, C Ravaglia, G Martignoni… - Biomedicines, 2022 - mdpi.com
Despite intense investigation, the pathogenesis of COVID-19 and the newly defined long
COVID-19 syndrome are not fully understood. Increasing evidence has been provided of …