Public health globally faces significant risks from conditions like acute respiratory distress
syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and various …

Mucosal surfaces are lined by epithelial cells, which provide a complex and adaptive
module that ensures first-line defense against external toxics, irritants, antigens, and …

Periodontal disease (PD) comprises a group of diseases involving inflammatory aspects of
the host and dysbiotic events that affect periodontal tissues and could have systemic …

Air− liquid interface (ALI) culture models currently represent a valid instrument to recreate
the typical aspects of the respiratory tract in vitro in both healthy and diseased state. They …

Tobacco smoking is a major cause of chronic obstructive pulmonary disease (COPD) and
atherosclerotic cardiovascular disease (ASCVD). These diseases share common …

Matrix metalloproteinases (MMPs) are proteolytic enzymes that degrade proteins of the
extracellular matrix and the basement membrane. Thus, these enzymes regulate airway …

Chronic obstructive pulmonary disease (COPD) affects the health of more than 300 million
people worldwide; at present, there is no effective drug to treat COPD. Smoking is the most …

Pulmonary fibrosis (PF) is a progressive, and life-threatening interstitial lung disease which
causes scarring in the lung parenchyma and thereby affects architecture and functioning of …

There is an increasing interest in biomarkers of nitric oxide dysregulation and oxidative
stress to guide management and identify new therapeutic targets in patients with chronic …

Objectives Chronic obstructive pulmonary disease (COPD) is a major cause of death
globally. Inflammation plays a crucial role in COPD development. Pyroptosis, an …