The orbitofrontal cortex and amygdala are involved in emotion and in motivation, but the
relationship between these functions performed by these brain structures is not clear. To …

While the amygdala is often implicated in the neurobiology of posttraumatic stress disorder
(PTSD), the pattern of results remains mixed. One reason for this may be the heterogeneity …

The multiple-memory-systems framework—that distinct types of memory are supported by
distinct brain systems—has guided learning and memory research for decades. However …

Depressive disorders are a leading cause of global disability, afflicting approximately 280
million individuals worldwide each year (1). In the United States, more than one in five …

Abstract MCGREGOR, MS, and RT LaLumiere. Still a “hidden island”? The rodent insular
cortex in drug seeking, reward, and risk. NEUROSCI BIOBEHAV REV 21 (1) XXX-XXX …

To thrive in challenging environments, individuals must pursue rewards while avoiding
threats. Extensive studies in animals and humans have identified the central extended …

Individuals typically want what they expect to like, often based on memories of previous
positive experiences. However, in some situations desire can decouple completely from …

Withdrawal from opioids involves a negative affective state that promotes maintenance of
drug-seeking behavior and relapse. As such, understanding the neurobiological …

To better understand the function of cholinergic projection neurons in the ventral pallidum
(VP), we examined behavioral responses to appetitive (APP) and aversive (AV) odors that …

The amygdala is a heterogeneous network of subcortical nuclei with central importance in
cognitive and clinical neuroscience. Various experimental designs in human psychology …