Membranous nephropathy: mechanistic insights and therapeutic perspectives

MR Hua, YL Zhao, JZ Yang, L Zou, YY Zhao… - International …, 2023 - Elsevier
Membranous nephropathy (MN) is one of the most common causes of non-diabetic
nephrotic syndrome in adults. About 80% of cases are renal limited (primary MN) and 20 …

[HTML][HTML] Experimental models for elderly patients with membranous nephropathy: Application and advancements

X Tang, H Dai, Y Hu, W Liu, Q Zhao, H Jiang… - Experimental …, 2024 - Elsevier
Membranous nephropathy (MN) occurs predominantly in middle-aged and elderly
individuals and ranks among the most prevalent etiologies of elderly nephrotic syndrome. As …

A nomogram prediction model for treatment failure in primary membranous nephropathy

C Geng, L Huang, Q Li, G Li, Y Li, P Zhang, Y Feng - Renal Failure, 2023 - Taylor & Francis
Background Primary membranous nephropathy (PMN) has a heterogeneous natural course.
Immunosuppressive therapy is recommended for PMN patients at moderate or high risk of …

[HTML][HTML] Activation of the IL-6/STAT3 pathway contributes to the pathogenesis of membranous nephropathy and is a target for Mahuang Fuzi and Shenzhuo Decoction …

Q Zhao, H Dai, H Jiang, N Zhang, F Hou… - Biomedicine & …, 2024 - Elsevier
Background Primary membranous nephropathy (PMN) is an autoimmune glomerular
disease. IL-6 is a potential therapeutic target for PMN. Previous clinical studies have …

The Value of Peripheral Blood Cell Ratios in Primary Membranous Nephropathy: A Single Center Retrospective Study

AH Zhang, GX Dai, QD Zhang, HD Huang… - Journal of Inflammation …, 2023 - Taylor & Francis
Background Primary membranous nephropathy (PMN) is a common cause of nephrotic
syndrome in adults. Forty percent of the patients continue to progress and eventually …

Circulating inflammatory proteins may be potential drug targets for Idiopathic Membranous Nephropathy: proteome-wide Mendelian Randomization and colocalization …

Z Su, Q Rao, D Wu, Z Yin, W Liu, Q Wan - medRxiv, 2023 - medrxiv.org
Background: Idiopathic membranous nephropathy (IMN) is a predominant cause of
nephrotic syndrome among adults. Existing drugs are ineffective in about one-third of IMN …

[HTML][HTML] Membranous nephropathy with systemic light-chain amyloidosis of remission after rituximab therapy: A case report

J Zhang, X Wang, GM Zou, JY Li… - World Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
BACKGROUND About 70%-80% of patients with primary membranous nephropathy (MN)
have phospholipase A2 receptor (PLA2R) in renal tissue. Systemic light-chain (AL) …