Thymic epithelial cells (TECs) are important for T cell development and immune tolerance
establishment. Although comprehensive molecular regulation of TEC development has …

Thymic epithelial cells (TECs) are essential in supporting the development of mature T cells
from hematopoietic progenitor cells and facilitate their lineage-commitment, proliferation, T …

Background Thymus hypoplasia due to stromal cell problems has been linked to mutations
in several transcription factors, including Forkhead box N1 (FOXN1). FOXN1 supports T-cell …

During embryonic development, several independent generations of hematopoietic cells
were identified. They occur in the yolk sac and the intra‐embryonic major arteries, in a …

Although some advances have been made in understanding the molecular regulation of
mTEC development, the role of epigenetic regulators in the development and maturation of …

Simple Summary Thymomas and thymic carcinomas (together referred to as thymic
epithelial tumors, TETs) are a heterogeneous group of rare tumors of the anterior …

Increasing studies show that gut microbiota play a central role in immunity, although the
impact of the microbiota on mediation of thymic T cells throughout life is not well understood …

Backgroud: Thymic atrophy marks the onset of immune aging, precipitating developmental
anomalies in T cells. Numerous clinical and preclinical investigations have underscored the …

It is well known that the most important feature of adaptive immunity is the specificity that
provides highly precise recognition of the self, altered-self, and non-self. Due to the high …

Syringic acid (SA), a naturally occurring phenolic substance present in many edible plants
and fruits, has been shown to have potential in immunoenhancement applications. In this …