Elderberry (Sambucus nigra L.) is rich in many bioactive compounds and exhibits diverse
health functions, of which an understanding can be helpful for its better utilization in the food …

It has long been known that endothelial Ca2+ signals drive angiogenesis by recruiting
multiple Ca2+-sensitive decoders in response to pro-angiogenic cues, such as vascular …

Background: Current paradigms suggest that nitric oxide (NO) produced by endothelial cells
(ECs) through endothelial nitric oxide synthase (eNOS) in the vessel wall is the primary …

A significant amount of clinical and research interest in thrombosis is focused on large
vessels (eg, stroke, myocardial infarction, deep venous thrombosis, etc.); however …

Dynamic changes in astrocyte free Ca 2+ regulate synaptic signaling and local blood flow.
Although astrocytes are poised to integrate signals from synapses and the vasculature to …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by severe joint damage
and disability. However, the specific mechanism of RA has not been thoroughly clarified …

The interplay between lncRNAs and miRNAs was reported to be associated with cerebral
ischemia reperfusion injury (CIRI). Besides, the lncRNA ZFAS1 was significantly …

Vascular dementia (VaD) is the second most common form of dementia worldwide. It is
caused by cerebrovascular disease, and patients often show severe impairments of …

Background: Neurovascular coupling (NVC) is the mechanism whereby an increase in
neuronal activity (NA) leads to local elevation in cerebral blood flow (CBF) to match the …

Nitric oxide synthases (NOS) are the major sources of nitric oxide (NO), a small bioactive
molecule involved in the regulation of many cellular processes. One of the most prominent …