[HTML][HTML] Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention

X Zhu, Z Chen, W Shen, G Huang, JM Sedivy… - Signal transduction and …, 2021 - nature.com
Remarkable progress in ageing research has been achieved over the past decades.
General perceptions and experimental evidence pinpoint that the decline of physical …

[HTML][HTML] Aging of mesenchymal stem cell: machinery, markers, and strategies of fighting

M Al-Azab, M Safi, E Idiiatullina, F Al-Shaebi… - Cellular & Molecular …, 2022 - Springer
Human mesenchymal stem cells (MSCs) are primary multipotent cells capable of
differentiating into osteocytes, chondrocytes, and adipocytes when stimulated under …

Amorphizing metal selenides-based ROS biocatalysts at surface nanolayer toward ultrafast inflammatory diabetic wound healing

Y Deng, Y Gao, T Li, S Xiao, M Adeli, RD Rodriguez… - ACS …, 2023 - ACS Publications
The microenvironments with high reactive-oxygen-species (ROS) levels, inflammatory
responses, and oxidative-stress effects in diabetic ulcer wounds, leading to poor …

[HTML][HTML] Mesenchymal stem cell-based therapy for cardiovascular disease: progress and challenges

L Bagno, KE Hatzistergos, W Balkan, JM Hare - Molecular Therapy, 2018 - cell.com
Administration of mesenchymal stem cells (MSCs) to diseased hearts improves cardiac
function and reduces scar. These effects occur via stimulation of endogenous repair …

Roles of extracellular vesicles in the aging microenvironment and age‐related diseases

Y Yin, H Chen, Y Wang, L Zhang… - Journal of extracellular …, 2021 - Wiley Online Library
Cellular senescence is a persistently hypoproliferative state with diverse stressors in a
specific aging microenvironment. Senescent cells have a double‐edged sword effect: they …

[HTML][HTML] The role of mitochondria in osteogenic, adipogenic and chondrogenic differentiation of mesenchymal stem cells

Q Li, Z Gao, Y Chen, MX Guan - Protein & cell, 2017 - Springer
Mesenchymal stem cells (MSCs) are progenitors of connective tissues, which have emerged
as important tools for tissue engineering due to their differentiation potential along various …

Multifaceted Catalytic ROS‐Scavenging via Electronic Modulated Metal Oxides for Regulating Stem Cell Fate

Q Tian, W Wang, L Cao, X Tian, G Tian… - Advanced …, 2022 - Wiley Online Library
Developing reactive oxygen species (ROS)‐scavenging nanostructures to protect and
regulate stem cells has emerged as an intriguing strategy for promoting tissue regeneration …

TLR4 downregulation by the RNA-binding protein PUM1 alleviates cellular aging and osteoarthritis

DS Yoon, KM Lee, Y Choi, EA Ko, NH Lee… - Cell Death & …, 2022 - nature.com
Dysfunction of mRNA or RNA-binding proteins (RBPs) causes cellular aging and age-
related degenerative diseases; however, information regarding the mechanism through …

Oral mesenchymal stem/progenitor cells: the immunomodulatory masters

L Zhou, W Liu, Y Wu, W Sun, CE Dörfer… - Stem cells …, 2020 - Wiley Online Library
Oral mesenchymal stem/progenitor cells (MSCs) are renowned in the field of tissue
engineering/regeneration for their multilineage differentiation potential and easy acquisition …

[HTML][HTML] The role and mechanism of mitochondrial functions and energy metabolism in the function regulation of the mesenchymal stem cells

W Yan, S Diao, Z Fan - Stem Cell Research & Therapy, 2021 - Springer
Mesenchymal stem cells (MSCs) are multipotent cells that show self-renewal, multi-
directional differentiation, and paracrine and immune regulation. As a result of these …